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Items: 4

1.

An Erratic Gene Expression Signature in Primary Hematopoietic Stem Cells: Implications for Interpretations of Aging

(Submitter supplied) A decline in hematopoietic stem cell (HSC) function is believed to underlie hematological shortcomings with age, but a comprehensive molecular understanding of these changes is currently lacking. Here, we provide evidence that a transcriptional signature reported in several prior studies on HSC aging is linked to stress-induced changes in gene expression rather than aging. Our findings have strong implications for the design and interpretation of HSC aging studies.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL24247
2 Samples
Download data: CSV, H5, RDS, TAR
Series
Accession:
GSE224590
ID:
200224590
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

HSPCs, HTO-derived cDNA

Organism:
Mus musculus
Source name:
Bone Marrow
Platform:
GPL24247
Series:
GSE224590
Download data
Sample
Accession:
GSM7026710
ID:
307026710
4.

HSPCs, mRNA-derived cDNA

Organism:
Mus musculus
Source name:
Bone Marrow
Platform:
GPL24247
Series:
GSE224590
Download data: CSV, H5, RDS, TAR
Sample
Accession:
GSM7026709
ID:
307026709
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Supplemental Content

db=gds|term=GSE224590[Accession]|query=1|qty=2|blobid=MCID_661930f36bc2bd5af48b0441|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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