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Items: 8

1.

Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3 [scRNA-seq]

(Submitter supplied) Split-Hand/Foot Malformation type 3 (SHFM3) is a congenital limb malformation associated with tandem duplications at the LBX1/FGF8 locus. Yet, the disease patho-mechanism remains unsolved. Here we investigated the functional consequences of SHFM3-associated rearrangements on chromatin conformation and gene expression in vivo in transgenic mice. We show that the Lbx1/Fgf8 locus consists of two separate, but interacting, regulatory domains. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16417
6 Samples
Download data: MTX, TSV
Series
Accession:
GSE223456
ID:
200223456
2.

Illumina MiSeq (Mus musculus)

Platform
Accession:
GPL16417
ID:
100016417
3.

scRNAseq-mm-Inv1-HL-E115-Rep1-L27833

Organism:
Mus musculus
Source name:
Hindlimb
Platform:
GPL16417
Series:
GSE197404 GSE223456
Download data
Sample
Accession:
GSM6956538
ID:
306956538
4.

scRNAseq-mm-Inv1-FL-E115-Rep1-L27832

Organism:
Mus musculus
Source name:
Forelimb
Platform:
GPL16417
Series:
GSE197404 GSE223456
Download data
Sample
Accession:
GSM6956537
ID:
306956537
5.

scRNAseq-mm-G4-HL-E115-Rep1-L27831

Organism:
Mus musculus
Source name:
Hindlimb
Platform:
GPL16417
Series:
GSE197404 GSE223456
Download data
Sample
Accession:
GSM6956536
ID:
306956536
6.

scRNAseq-mm-G4-FL-E115-Rep1-L27830

Organism:
Mus musculus
Source name:
Forelimb
Platform:
GPL16417
Series:
GSE197404 GSE223456
Download data
Sample
Accession:
GSM6956535
ID:
306956535
7.

scRNAseq-mm-Dup-HL-E115-Rep1-L20667

Organism:
Mus musculus
Source name:
Hindlimb
Platform:
GPL16417
Series:
GSE197404 GSE223456
Download data
Sample
Accession:
GSM6956534
ID:
306956534
8.

scRNAseq-mm-Wt-HL-E115-Rep1-L20666

Organism:
Mus musculus
Source name:
Hindlimb
Platform:
GPL16417
Series:
GSE197404 GSE223456
Download data
Sample
Accession:
GSM6956533
ID:
306956533
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Supplemental Content

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