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Items: 9

1.

BRWD1 orchestrates chromatin topology by converting static to dynamic cohesin complexes (Hi-C)

(Submitter supplied) Lymphocyte development consists of sequential and mutually exclusive cell states of proliferative selection and antigen receptor gene recombination. Transitions between each state require large, coordinated changes in epigenetic landscapes and transcriptional programs. How this occurs remains unclear. Herein, we demonstrate that in small pre-B cells, the lineage and stage-specific epigenetic reader BRWD1 reorders three-dimensional chromatin topology to affect transition between proliferative and gene recombination molecular programs. more...
Organism:
Mus musculus
Type:
Other
Platforms:
GPL24247 GPL21103
6 Samples
Download data: HIC
Series
Accession:
GSE221517
ID:
200221517
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
4.

SpreB-WT.2

Organism:
Mus musculus
Source name:
Small_Pre-B_cell
Platform:
GPL24247
Series:
GSE221517 GSE221519
Download data: HIC
Sample
Accession:
GSM6879753
ID:
306879753
5.

SpreB-Brwd1KO.2

Organism:
Mus musculus
Source name:
Small_Pre-B_cell
Platform:
GPL24247
Series:
GSE221517 GSE221519
Download data: HIC
Sample
Accession:
GSM6879751
ID:
306879751
6.

ImmatureB.2

Organism:
Mus musculus
Source name:
Immuture B cell
Platform:
GPL24247
Series:
GSE221517 GSE221519
Download data: HIC
Sample
Accession:
GSM6879749
ID:
306879749
7.

SpreB-WT.1

Organism:
Mus musculus
Source name:
Small_Pre-B_cell
Platform:
GPL21103
Series:
GSE221517 GSE221519
Download data: HIC
Sample
Accession:
GSM6879752
ID:
306879752
8.

SpreB-Brwd1KO.1

Organism:
Mus musculus
Source name:
Small_Pre-B_cell
Platform:
GPL21103
Series:
GSE221517 GSE221519
Download data: HIC
Sample
Accession:
GSM6879750
ID:
306879750
9.

ImmatureB.1

Organism:
Mus musculus
Source name:
Immuture B cell
Platform:
GPL21103
Series:
GSE221517 GSE221519
Download data: HIC
Sample
Accession:
GSM6879748
ID:
306879748
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Supplemental Content

db=gds|term=GSE221517[Accession]|query=1|qty=2|blobid=MCID_66df4f8f3ec0504f942598a1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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