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Items: 6

1.

Single-cell RNA-seq uncovers unique gene expression profiles in the spleen of hypoxic mice

(Submitter supplied) The stability of FOXP3 expression in Tregs influences the balance between tolerance and autoimmunity. Treg cell development and function are regulated by IL-2, which binds to IL-2Rα (also called CD25). Decreased expression of CD25 (Il2ra gene) characterizes Tregs that lose FOXP3 expression (exTregs) and undergo transdifferentiation into TH17 cells. This has been established under arthritic conditions but whether this Treg transdifferenciation into exTregs occur following hypoxia exposure, it is unknown. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
4 Samples
Download data: MTX, RDATA, TSV
Series
Accession:
GSE219259
ID:
200219259
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

FOXP3_GFP_Tom_WPRE_Sample4

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE219259
Download data: TSV
Sample
Accession:
GSM6779282
ID:
306779282
4.

FOXP3_GFP_Tom_WPRE_Sample3

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE219259
Download data: MTX, TSV
Sample
Accession:
GSM6779281
ID:
306779281
5.

FOXP3_GFP_Tom_WPRE_Sample2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE219259
Download data: MTX, TSV
Sample
Accession:
GSM6779280
ID:
306779280
6.

FOXP3_GFP_Tom_WPRE_Sample1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE219259
Download data: MTX, TSV
Sample
Accession:
GSM6779279
ID:
306779279
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Supplemental Content

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