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Items: 15

1.

RNAseq and scRNAseq analysis of UPFL mouse tumors

(Submitter supplied) Fibroblast growth factor receptor 3 (FGFR3) is altered in up to 50% of urothelial cancers (UC), yet its functional impact is not fully understood. We generated a Cre-inducible FGFR3 S249C allele (LSL-FGFR3 S249C) to understand the functional impact of FGFR3 activation on UC biology, the immune microenvironment, and how FGFR inhibition combines with PD1 immune checkpoint inhibition (ICI). Uroplakin3a (Upk3a) driven expression of Trp53 R270H and FGFR3 S249C (UPFL) promoted tumor formation.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL19057
12 Samples
Download data: H5, TXT
Series
Accession:
GSE217093
ID:
200217093
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

WYKNIU2

Organism:
Mus musculus
Source name:
scraped urothelium
Platform:
GPL24247
Series:
GSE217093
Download data: H5
Sample
Accession:
GSM7763800
ID:
307763800
5.

UPFL7

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL19057
Series:
GSE217093
Download data
Sample
Accession:
GSM6704999
ID:
306704999
6.

UPFL6

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL19057
Series:
GSE217093
Download data
Sample
Accession:
GSM6704998
ID:
306704998
7.

UPFL5

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL19057
Series:
GSE217093
Download data
Sample
Accession:
GSM6704997
ID:
306704997
8.

UPFL4

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL19057
Series:
GSE217093
Download data
Sample
Accession:
GSM6704996
ID:
306704996
9.

UPFL3

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL19057
Series:
GSE217093
Download data
Sample
Accession:
GSM6704995
ID:
306704995
10.

UPFL2

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL19057
Series:
GSE217093
Download data
Sample
Accession:
GSM6704994
ID:
306704994
11.

UPFL1

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL19057
Series:
GSE217093
Download data
Sample
Accession:
GSM6704993
ID:
306704993
12.

UPFL_506_Erdafitinib_Primary

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL24247
Series:
GSE217093
Download data: H5
Sample
Accession:
GSM6705003
ID:
306705003
13.

UPFL_517_Erdafitinib_Primary

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL24247
Series:
GSE217093
Download data: H5
Sample
Accession:
GSM6705002
ID:
306705002
14.

UPFL_361_Primary

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL24247
Series:
GSE217093
Download data: H5
Sample
Accession:
GSM6705001
ID:
306705001
15.

UPFL_369_Primary

Organism:
Mus musculus
Source name:
bladder tumor
Platform:
GPL24247
Series:
GSE217093
Download data: H5
Sample
Accession:
GSM6705000
ID:
306705000
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Supplemental Content

db=gds|term=GSE217093[Accession]|query=1|qty=2|blobid=MCID_66951b9c097f457047a86310|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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