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1.

Effects of DAC treatment

(Submitter supplied) Reversal of gene promoter DNA hypermethylation and associated abnormal gene silencing is an attractive approach to cancer therapy. The DNA methylation inhibitor, decitabine (5-aza-2'-deoxycitidine), is proving efficacious for hematological neoplasms especially at lower, less toxic, doses. Experimentally, high doses induce rapid DNA damage and cytotoxicity, but these may not explain the prolonged time to response seen in patients. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by array
4 related Platforms
55 Samples
Download data: TXT
Series
Accession:
GSE20945
ID:
200020945

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...
Organism:
Homo sapiens
21 DataSets
939 Series
4 Related Platforms
24778 Samples
Download data
Platform
Accession:
GPL6480
ID:
100006480

3.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...
Organism:
Homo sapiens
10 DataSets
834 Series
3 Related Platforms
15348 Samples
Download data: TXT
Platform
Accession:
GPL4133
ID:
100004133

4.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website
Organism:
Homo sapiens
1647 Series
1 Related Platform
117274 Samples
Download data: BPM, CSV, TXT, XLSX
Platform
Accession:
GPL13534
ID:
100013534

5.

Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2)

(Submitter supplied) HumanMethylation27 DNA Analysis BeadChip allows researchers to interrogate 27,578 highly informative CpG sites per sample at single-nucleotide resolution. This 12-sample BeadChip features content derived from the well-annotated NCBI CCDS database (Genome Build 36) and is supplemented with more than 1,000 cancer-related genes described in published literature. Probe content has been enriched to deeply cover more than 150 well-established cancer genes known to show differential methylation patterns. more...
Organism:
Homo sapiens
347 Series
19056 Samples
Download data: CSV
Platform
Accession:
GPL8490
ID:
100008490

6.

KG1A 10nM DAC day14 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated KG1A (channel 1) 10nM DAC, day14, Treated KG1A (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523771
ID:
300523771

7.

KG1A 10nM DAC day7 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated KG1A (channel 1) 10nM DAC, day7, Treated KG1A (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523770
ID:
300523770

8.

KG1A 10nM DAC day3 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated KG1A (channel 1) 10nM DAC, day3, Treated KG1A (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523742
ID:
300523742

9.

MCF7 100nM DAC day10 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated MCF7 (channel 1) 100nM DAC, day10, Treated MCF7 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523727
ID:
300523727

10.

MCF7 100nM DAC day3 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated MCF7 (channel 1) 100nM DAC, day3, Treated MCF7 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523726
ID:
300523726

11.

MCF7 100nM DAC day1 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated MCF7 (channel 1) 100nM DAC, day1, Treated MCF7 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523725
ID:
300523725

12.

Kasumi-1 300nM TSA 9 hours [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated Kasumi-1 (channel 1) 300nM TSA, 9 hours, Treated Kasumi-1 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523724
ID:
300523724

13.

Kasumi-1 100nM ARA-C day3 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated Kasumi-1 (channel 1) 100nM ARA-C, day3, Treated Kasumi-1 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523723
ID:
300523723

14.

Kasumi-1 500nM DAC day3 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated Kasumi-1 (channel 1) 500nM DAC, day3, Treated Kasumi-1 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523722
ID:
300523722

15.

Kasumi-1 10nM DAC day3 (repeat) [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated Kasumi-1 (channel 1) 10nM DAC, day3, Treated Kasumi-1 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523721
ID:
300523721

16.

Kasumi-1 10nM DAC day14 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated Kasumi-1 (channel 1) 10nM DAC, day14, Treated Kasumi-1 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523720
ID:
300523720

17.

Kasumi-1 10nM DAC day7 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated Kasumi-1 (channel 1) 10nM DAC, day7, Treated Kasumi-1 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523701
ID:
300523701

18.

Kasumi-1 10nM DAC day3 [mRNA profiling]

Organism:
Homo sapiens
Source name:
Mock Treated Kasumi-1 (channel 1) 10nM DAC, day3, Treated Kasumi-1 (channel 2)
Platform:
GPL4133
Series:
GSE20945
Download data: TXT
Sample
Accession:
GSM523700
ID:
300523700

19.

Kasumi-1 leukemia cell line - 10nM DAC treated - day 3, rep2 [CH3'n profiling]

Organism:
Homo sapiens
Source name:
Kasumi-1 leukemia cell line, DAC treated
Platform:
GPL8490
Series:
GSE20945
Download data
Sample
Accession:
GSM618248
ID:
300618248

20.

Kasumi-1 leukemia cell line - Untreated - rep2 [CH3'n profiling]

Organism:
Homo sapiens
Source name:
Kasumi-1 leukemia cell line
Platform:
GPL8490
Series:
GSE20945
Download data
Sample
Accession:
GSM618247
ID:
300618247

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