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Items: 12

1.

Insm1 regulates the expression of thymic tissue-restricted antigens and the immune tolerance [CUT&Tag]

(Submitter supplied) Insm1, encoding a zinc finger protein, is expressed specifically in neuroendocrine cells. Recent study showed the first evidence of Insm1 expression in medullary thymic epithelial cells (mTEC). Here we investigated the expression and function of Insm1 in mTEC. Mutation of Insm1 resulted in decreased proportion of mTEChi although normal development of other types of thymic cells. We detected altered expression of a subset of tissue-restricted antigens (TRAs) and mild decreased expression of Aire and Fezf2 in Insm1 mutant mTEC. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
10 Samples
Download data: BW
Series
Accession:
GSE193926
ID:
200193926

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
13498 Series
684837 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

CUTandTag_IgG_mouse_adult_mTEC_rep2

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924343
ID:
306924343

SRA Run Selector

4.

CUTandTag_IgG_mouse_adult_mTEC_rep1

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924342
ID:
306924342

SRA Run Selector

5.

CUTandTag_Insm1_mouse_adult_mTEC_rep2

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924341
ID:
306924341

SRA Run Selector

6.

CUTandTag_Insm1_mouse_adult_mTEC_rep1

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924340
ID:
306924340

SRA Run Selector

7.

CUTandTag_IgG_mouse_E18.5_mTEC_rep3

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924339
ID:
306924339

SRA Run Selector

8.

CUTandTag_IgG_mouse_E18.5_mTEC_rep2

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924338
ID:
306924338

SRA Run Selector

9.

CUTandTag_IgG_mouse_E18.5_mTEC_rep1

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924337
ID:
306924337

SRA Run Selector

10.

CUTandTag_Insm1_mouse_E18.5_mTEC_rep3

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924336
ID:
306924336

SRA Run Selector

11.

CUTandTag_Insm1_mouse_E18.5_mTEC_rep2

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924335
ID:
306924335

SRA Run Selector

12.

CUTandTag_Insm1_mouse_E18.5_mTEC_rep1

Organism:
Mus musculus
Source name:
medullary thymic epithelial cells
Platform:
GPL24247
Series:
GSE193926 GSE193929
Download data: BW
Sample
Accession:
GSM6924334
ID:
306924334

SRA Run Selector

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