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Items: 4

1.

Single-cell multi-modal profiling of proteins and chromatin accessibility using PHAGE-ATAC [Intracellular_GFP]

(Submitter supplied) Multi-modal measurements of single cell profiles are a powerful tool for characterizing cell states and regulatory mechanisms. While current methods allow profiling of RNA along with either readouts of chromatin or protein, connecting chromatin state to protein levels remains a barrier. Here, we developed PHAGE-ATAC, a method that uses engineered camelid single-domain antibody (‘nanobody’)-displaying phages for simultaneous single-cell measurement of surface proteins, chromatin accessibility profiles, and mtDNA-based clonal tracing through a single-cell and massively parallel droplet-based assay of transposase-accessible chromatin with sequencing (ATAC-seq). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
Platform:
GPL21697
2 Samples
Download data: CSV, TSV
Series
Accession:
GSE172921
ID:
200172921
2.

NextSeq 550 (Homo sapiens)

Platform
Accession:
GPL21697
ID:
100021697
3.

Intracellular_GFP_Phage

Organism:
Homo sapiens
Source name:
HEK293T cells
Platform:
GPL21697
Series:
GSE157486 GSE172921
Download data
Sample
Accession:
GSM5259072
ID:
305259072
4.

Intracellular_GFP_ATAC

Organism:
Homo sapiens
Source name:
HEK293T cells
Platform:
GPL21697
Series:
GSE157486 GSE172921
Download data
Sample
Accession:
GSM5259071
ID:
305259071
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Supplemental Content

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