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Items: 1 to 20 of 38

1.

Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells(ATAC-seq)

(Submitter supplied) Hematopoietic stem cells (HSCs) exhibit considerable cell-intrinsic changes with age. Here, we performed an integrated analysis of transcriptome and chromatin accessibility of aged HSCs and downstream progenitors. Alterations in chromatin accessibility preferentially took place in HSCs with aging, which gradually resolved with differentiation. Differentially open accessible regions (open DARs) in aged HSCs showed enrichment of binding motifs of the STAT, ATF, and CNC family transcription factors that are activated in response to external stresses, and most of them comprised active, primed , and inactive enhancers. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18480
36 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE162551
ID:
200162551
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

aged CLP rep2

Organism:
Mus musculus
Source name:
20 month common lymphoid progenitor
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954127
ID:
304954127
4.

aged CLP rep1

Organism:
Mus musculus
Source name:
20 month common lymphoid progenitor
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954126
ID:
304954126
5.

aged MEP rep2

Organism:
Mus musculus
Source name:
20 month megakaryocyte-erythrocyte progenitors
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954125
ID:
304954125
6.

aged MEP rep1

Organism:
Mus musculus
Source name:
20 month megakaryocyte-erythrocyte progenitors
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954124
ID:
304954124
7.

aged GMP rep2

Organism:
Mus musculus
Source name:
20 month granulocyte-macrophage progenitors
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954123
ID:
304954123
8.

aged GMP rep1

Organism:
Mus musculus
Source name:
20 month granulocyte-macrophage progenitors
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954122
ID:
304954122
9.

aged MPP4 rep2

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 4s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954121
ID:
304954121
10.

aged MPP4 rep1

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 4s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954120
ID:
304954120
11.

aged MPP3 rep2

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 3s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954119
ID:
304954119
12.

aged MPP3 rep1

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 3s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954118
ID:
304954118
13.

aged MPP2 rep2

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 2s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954117
ID:
304954117
14.

aged MPP2 rep1

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 2s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954116
ID:
304954116
15.

aged MPP1 rep2

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 1s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954115
ID:
304954115
16.

aged MPP1 rep1

Organism:
Mus musculus
Source name:
20 month multipotent progenitor 1s
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954114
ID:
304954114
17.

aged HSC rep4

Organism:
Mus musculus
Source name:
20 month hematopoietic stem cells
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954113
ID:
304954113
18.

aged HSC rep3

Organism:
Mus musculus
Source name:
20 month hematopoietic stem cells
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954112
ID:
304954112
19.

aged HSC rep2

Organism:
Mus musculus
Source name:
20 month hematopoietic stem cells
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954111
ID:
304954111
20.

aged HSC rep1

Organism:
Mus musculus
Source name:
20 month hematopoietic stem cells
Platform:
GPL18480
Series:
GSE162551 GSE162662
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4954110
ID:
304954110
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