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Items: 12

1.

Transcriptome analysis using Quant-RNAseq after NPM1 or HIF-1α silencing under normoxia or Hypoxia

(Submitter supplied) Hypoxia inducible factor-1 (HIF-1) is a central transcriptional regulator of genes associated with adaptive responses to hypoxia. NPM1 is a histone chaperone found to associate with HIF-1α in a phosphorylation dependent manner and increase its activty. The aim of this study was to find if HIF-1α and NPM1 regualate gene expression under hypoxia. Transcriptome analysis using Quant-RNA-seq after HIF-1α or NPM1 silencing under hypoxia reveals a significant number of genes, the hypoxic expression of which depends on both proteins.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17303
10 Samples
Download data: TXT
2.

Ion Torrent Proton (Homo sapiens)

Platform
Accession:
GPL17303
ID:
100017303
3.

siHIF-1α Hypoxia rep2

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815232
ID:
304815232
4.

siHIF-1α Hypoxia rep1

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815231
ID:
304815231
5.

siNPM1 Hypoxia rep2

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815230
ID:
304815230
6.

siNPM1 Hypoxia rep1

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815229
ID:
304815229
7.

siNPM1 Normoxia rep2

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815228
ID:
304815228
8.

siNPM1 Normoxia rep1

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815227
ID:
304815227
9.

Nt Hypoxia rep2

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815226
ID:
304815226
10.

Nt Hypoxia rep1

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815225
ID:
304815225
11.

Nt Normoxia rep2

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815224
ID:
304815224
12.

Nt Normoxia rep1

Organism:
Homo sapiens
Source name:
HeLa cell line
Platform:
GPL17303
Series:
GSE158890
Download data
Sample
Accession:
GSM4815223
ID:
304815223
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Supplemental Content

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