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Items: 1 to 20 of 23

1.

Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos [ES cell RNA-seq]

(Submitter supplied) N6-methyladenosine (m6A) on chromosome-associated regulatory RNAs (carRNAs), including repeat RNAs, plays important roles in tuning the chromatin state and transcription, but the intrinsic mechanism remains unclear. Here, we report that YTHDC1 plays indispensable roles in the embryonic stem cell (ESC) self-renewal and differentiation potency, which highly depends on its m6A-binding ability. Ythdc1 is required for sufficient rRNA synthesis and repression of the 2-cell transcriptional program in ESCs, which recapitulates the transcriptome regulation by the LINE1 scaffold. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
21 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE157262
ID:
200157262

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
13444 Series
684249 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

RNA_ESC_Mettl3KO_3

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM5225922
ID:
305225922

SRA Run Selector

4.

RNA_ESC_Mettl3KO_2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM5225921
ID:
305225921

SRA Run Selector

5.

RNA_ESC_Mettl3KO_1

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM5225920
ID:
305225920

SRA Run Selector

6.

RNA_ESC_WT_3

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM5225919
ID:
305225919

SRA Run Selector

7.

RNA_ESC_WT_2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM5225918
ID:
305225918

SRA Run Selector

8.

RNA_ESC_WT_1

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM5225917
ID:
305225917

SRA Run Selector

9.

RNA_ESC_shKap1_2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760336
ID:
304760336

SRA Run Selector

10.

RNA_ESC_shKap1_1

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760335
ID:
304760335

SRA Run Selector

11.

RNA_ESC_shCtrl_2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760334
ID:
304760334

SRA Run Selector

12.

RNA_ESC_shCtrl_1

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760333
ID:
304760333

SRA Run Selector

13.

RNA_ESC_wtRes_3

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760332
ID:
304760332

SRA Run Selector

14.

RNA_ESC_wtRes_2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760331
ID:
304760331

SRA Run Selector

15.

RNA_ESC_wtRes_1

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760330
ID:
304760330

SRA Run Selector

16.

RNA_ESC_W378A_3

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760329
ID:
304760329

SRA Run Selector

17.

RNA_ESC_W378A_2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760328
ID:
304760328

SRA Run Selector

18.

RNA_ESC_W378A_1

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760327
ID:
304760327

SRA Run Selector

19.

RNA_ESC_Ythdc1KO_3

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760326
ID:
304760326

SRA Run Selector

20.

RNA_ESC_Ythdc1KO_2

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE157262 GSE157268
Download data: FPKM_TRACKING
Sample
Accession:
GSM4760325
ID:
304760325

SRA Run Selector

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db=gds|term=GSE157262[Accession]|query=1|qty=2|blobid=MCID_66e2c5409fd03c7db3a92d24|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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