GSE154741[Accession] - GEO DataSets - NCBI

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Select item 2001547411.

Autocrine vitamin D signaling switches off pro-inflammatory programs of Th1 cells

(Submitter supplied) The molecular mechanisms governing orderly shutdown and retraction of CD4+ T helper (Th)1 responses remain poorly understood. Here, we show that complement triggers contraction of Th1 responses by inducing intrinsic expression of the vitamin D (VitD) receptor (VDR) and the VitD-activating enzyme CYP27B1, permitting T cells to both activate and respond to VitD. VitD then initiated transition from pro-inflammatory IFN-γ+ Th1 cells to suppressive IL-10+ cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Other

Platforms:: GPL24676 GPL21290
45 Samples

Download data: BED, BW, TXT, XLSX

Series

Accession:: GSE154741

ID:: 200154741

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000246762.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

16543 Series
922800 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 1000212903.

Illumina HiSeq 3000 (Homo sapiens)

Organism:: Homo sapiens

1136 Series
28205 Samples

Platform

Accession:: GPL21290

ID:: 100021290

Select item 3056277784.

IgG Carrier CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM5627778

ID:: 305627778

SRA Run Selector

Select item 3056277775.

IgG VitD CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM5627777

ID:: 305627777

SRA Run Selector

Select item 3056277766.

BACH2 Carrier CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM5627776

ID:: 305627776

SRA Run Selector

Select item 3056277757.

BACH2 VitD CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BED, BW

Sample

Accession:: GSM5627775

ID:: 305627775

SRA Run Selector

Select item 3056277748.

STAT3 Carrier CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM5627774

ID:: 305627774

SRA Run Selector

Select item 3056277739.

STAT3 VitD CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BED, BW

Sample

Accession:: GSM5627773

ID:: 305627773

SRA Run Selector

Select item 30562777210.

VDR Carrier CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM5627772

ID:: 305627772

SRA Run Selector

Select item 30562777111.

VDR VitD CUT&Tag 96hr

Organism:: Homo sapiens

Source name:: Isolated and Treated Memory CD4+ Cells (Negative Magnetic Selection)

Platform:: GPL24676
Series:: GSE154741

Download data: BED, BW

Sample

Accession:: GSM5627771

ID:: 305627771

SRA Run Selector

Select item 30467808812.

VitD Treated Healthy Donor IgG CUT&RUN 72hr

Organism:: Homo sapiens

Source name:: VitD Treated Healthy Donor IgG CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678088

ID:: 304678088

SRA Run Selector

Select item 30467808713.

VitD Treated Healthy Donor IgG CUT&RUN 48hr

Organism:: Homo sapiens

Source name:: VitD Treated Healthy Donor IgG CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678087

ID:: 304678087

SRA Run Selector

Select item 30467808614.

VitD Treated Healthy Donor IgG CUT&RUN .75hr

Organism:: Homo sapiens

Source name:: VitD Treated Healthy Donor IgG CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678086

ID:: 304678086

SRA Run Selector

Select item 30467808515.

Carrier Treated Healthy Donor IgG CUT&RUN 72hr

Organism:: Homo sapiens

Source name:: Carrier Treated Healthy Donor IgG CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678085

ID:: 304678085

SRA Run Selector

Select item 30467808416.

Carrier Treated Healthy Donor IgG CUT&RUN 48hr

Organism:: Homo sapiens

Source name:: Carrier Treated Healthy Donor IgG CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678084

ID:: 304678084

SRA Run Selector

Select item 30467808317.

Carrier Treated Healthy Donor IgG CUT&RUN .75hr

Organism:: Homo sapiens

Source name:: Carrier Treated Healthy Donor IgG CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678083

ID:: 304678083

SRA Run Selector

Select item 30467808218.

VitD Treated Healthy Donor c-JUN CUT&RUN 72hr

Organism:: Homo sapiens

Source name:: VitD Treated Healthy Donor c-JUN CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678082

ID:: 304678082

SRA Run Selector

Select item 30467808119.

VitD Treated Healthy Donor c-JUN CUT&RUN 48hr

Organism:: Homo sapiens

Source name:: VitD Treated Healthy Donor c-JUN CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678081

ID:: 304678081

SRA Run Selector

Select item 30467808020.

VitD Treated Healthy Donor c-JUN CUT&RUN .75hr

Organism:: Homo sapiens

Source name:: VitD Treated Healthy Donor c-JUN CUT&RUN

Platform:: GPL24676
Series:: GSE154741

Download data: BW

Sample

Accession:: GSM4678080

ID:: 304678080

SRA Run Selector

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