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Items: 18

1.

mTORC1 and B cell survival signal regulate formation of memory precursors in the germinal center [2]

(Submitter supplied) A still unanswered question is what drives the small fraction of activated germinal center (GC) B cells that survive to become long-lived quiescent memory B cells. We found here that a small population of light zone GC cells (CD38intBcl6hi/intEfnb1+) with lower mTORC1 activity favored the memory B cell fate. Constitutively high mTORC1 activity led to defects in formation of the CD38intBcl6hi/intEfnb1+ cells; conversely, decreasing mTORC1 activity resulted in relative enrichment of this memory-prone GC population over the recycling-prone one. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18480
16 Samples
Download data: TXT
Series
Accession:
GSE147095
ID:
200147095
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

Fraction 7#3

Organism:
Mus musculus
Source name:
Fraction 7 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417010
ID:
304417010
4.

Fraction 7#2

Organism:
Mus musculus
Source name:
Fraction 7 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417009
ID:
304417009
5.

Fraction 7#1

Organism:
Mus musculus
Source name:
Fraction 7 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417008
ID:
304417008
6.

Fraction 6#2

Organism:
Mus musculus
Source name:
Fraction 6 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417007
ID:
304417007
7.

Fraction 6#1

Organism:
Mus musculus
Source name:
Fraction 6 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417006
ID:
304417006
8.

Fraction 5#3

Organism:
Mus musculus
Source name:
Fraction 5 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417005
ID:
304417005
9.

Fraction 5#2

Organism:
Mus musculus
Source name:
Fraction 5 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417004
ID:
304417004
10.

Fraction 5#1

Organism:
Mus musculus
Source name:
Fraction 5 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417003
ID:
304417003
11.

Fraction 3#3

Organism:
Mus musculus
Source name:
Fraction 3 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417002
ID:
304417002
12.

Fraction 3#2

Organism:
Mus musculus
Source name:
Fraction 3 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417001
ID:
304417001
13.

Fraction 3#1

Organism:
Mus musculus
Source name:
Fraction 3 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4417000
ID:
304417000
14.

Fraction 2#2

Organism:
Mus musculus
Source name:
Fraction 2 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4416998
ID:
304416998
15.

Fraction 2#1

Organism:
Mus musculus
Source name:
Fraction 2 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4416997
ID:
304416997
16.

LZ#3

Organism:
Mus musculus
Source name:
GC LZ B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4416996
ID:
304416996
17.

LZ#2

Organism:
Mus musculus
Source name:
GC LZ B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4416995
ID:
304416995
18.

LZ#1

Organism:
Mus musculus
Source name:
GC LZ B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
Download data
Sample
Accession:
GSM4416994
ID:
304416994
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Supplemental Content

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