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Items: 11

1.

Effects of Different Doses of rAAV 5-mCherry on Transcriptome of Hippocampal Pyramidal Neurons in Male Mouse

(Submitter supplied) Purpose: Here, we evaluated the effects of three different doses of rAAV5 vectors, which are widely used for functional studies in the brain, on hippocampal pyramidal neurons transcription in male mice. Results: There was a strong correlation between rAAV dose and toxicity. As dose increased, rAAV5-DIO-mCherry upregulated genes related to the immune and inflammation response and neuron death and downregulated genes associated with the synapse and axon compartments, mitochondrial potein complex suggesting that higher dose rAAV 5-DIO-mCherry may induce pyramidal neuronal fragility and impair synaptic transmission and structure. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
9 Samples
Download data: TXT, XLS
Series
Accession:
GSE139997
ID:
200139997
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

S1009

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151322
ID:
304151322
4.

S1008

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151321
ID:
304151321
5.

S1007

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151320
ID:
304151320
6.

S1006

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151319
ID:
304151319
7.

S1005

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151318
ID:
304151318
8.

S1004

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151317
ID:
304151317
9.

S1003

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151316
ID:
304151316
10.

S1002

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151315
ID:
304151315
11.

S1001

Organism:
Mus musculus
Source name:
Hippo Pyramidal neruon
Platform:
GPL21273
Series:
GSE139997
Download data: TXT
Sample
Accession:
GSM4151314
ID:
304151314
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Supplemental Content

db=gds|term=GSE139997[Accession]|query=1|qty=2|blobid=MCID_664baf388e57fe2577419c83|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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