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Items: 1 to 20 of 226

1.

EED is required for Mouse Primordial Germ Cell Differentiation in the Embryonic Gonad

(Submitter supplied) Development of Primordial germ cells (PGCs) is required for reproduction. During PGC development in mammals, major epigenetic remodeling occurs which is hypothesized to establish an epigenetic landscape for sex-specific germ cell differentiation and gametogenesis. In order to address the role of Embryonic Ectoderm Development (EED) and Histone 3 lysine 27 trimethylation (H3K27me3) in this process, we created a conditional deletion in EED and show that EED is essential for regulating the timing of sex-specific PGC differentiation in both ovaries and testes, as well as X chromosome dosage decompensation in testes. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL17021 GPL24247 GPL21103
222 Samples
Download data: CGMAP, TXT
Series
Accession:
GSE139413
ID:
200139413
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
4.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
5.

WGBS_E11.5_XX_ECKO_Rep_2

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data: CGMAP
Sample
Accession:
GSM5733159
ID:
305733159
6.

WGBS_E11.5_XX_ECKO_Rep_1

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data: CGMAP
Sample
Accession:
GSM5733158
ID:
305733158
7.

WGBS_E11.5_XX_Control_Rep_1

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data: CGMAP
Sample
Accession:
GSM5733157
ID:
305733157
8.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_1

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505065
ID:
305505065
9.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_4

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505064
ID:
305505064
10.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_2

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505063
ID:
305505063
11.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_5

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505062
ID:
305505062
12.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_3

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505061
ID:
305505061
13.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_6

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505060
ID:
305505060
14.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_7

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505059
ID:
305505059
15.

scRNA-seq_E12-5_XY_Control_Embryo_2_Rep_8

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505058
ID:
305505058
16.

scRNA-seq_E12-5_XY_ECKO_Embryo_2_Rep_17

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505057
ID:
305505057
17.

RNA-seq_E13.5_XY_ECKO_Rep_3

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL17021
Series:
GSE139413
Download data
Sample
Accession:
GSM5504868
ID:
305504868
18.

scRNA-seq_E12-5_XY_ECKO_Embryo_2_Rep_20

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505056
ID:
305505056
19.

RNA-seq_E13.5_XY_ECKO_Rep_2

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL17021
Series:
GSE139413
Download data
Sample
Accession:
GSM5504867
ID:
305504867
20.

scRNA-seq_E12-5_XY_ECKO_Embryo_2_Rep_18

Organism:
Mus musculus
Source name:
Primordial germ cells
Platform:
GPL24247
Series:
GSE139413
Download data
Sample
Accession:
GSM5505055
ID:
305505055
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Supplemental Content

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