U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 43

1.

Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties

(Submitter supplied) Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population. Currently, it is unclear whether advanced donor age and commonly associated comorbidities affect the properties of ex vivo-expanded BMSCs. Thus, we stratified cells from adult and elderly donors from our biobank (n = 10 and n = 13, mean age 38 and 72 years, respectively) and compared their phenotypic and functional performance, using multiple assays typically employed as minimal criteria for defining multipotent mesenchymal stromal cells (MSCs).We found that BMSCs from both cohorts meet the standard criteria for MSC, exhibiting similar morphology, growth kinetics, gene expression profiles, and pro-angiogenic and immunosuppressive potential and the capacity to differentiate toward adipogenic, chondrogenic, and osteogenic lineages.We found no substantial differences between cells from the adult and elderly cohorts. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18460 GPL20301
40 Samples
Download data: TXT
2.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
3.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
4.

Bone marrow stromal cells, S5545

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128727
ID:
304128727
5.

Bone marrow stromal cells, S5682

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128726
ID:
304128726
6.

Bone marrow stromal cells, S5681

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128725
ID:
304128725
7.

Bone marrow stromal cells, S5548

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128724
ID:
304128724
8.

Bone marrow stromal cells, S5546

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128723
ID:
304128723
9.

Bone marrow stromal cells, S5547

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128722
ID:
304128722
10.

Bone marrow stromal cells, S5537

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128721
ID:
304128721
11.

Bone marrow stromal cells, S5544

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128720
ID:
304128720
12.

Bone marrow stromal cells, S5680

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128719
ID:
304128719
13.

Bone marrow stromal cells, S5536

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128718
ID:
304128718
14.

Bone marrow stromal cells, S5535

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128717
ID:
304128717
15.

Bone marrow stromal cells, S5676

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128716
ID:
304128716
16.

Bone marrow stromal cells, S5531

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128715
ID:
304128715
17.

Bone marrow stromal cells, S5538

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128714
ID:
304128714
18.

Bone marrow stromal cells, S5532

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128713
ID:
304128713
19.

Bone marrow stromal cells, S5675

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128712
ID:
304128712
20.

Bone marrow stromal cells, S5530

Organism:
Homo sapiens
Source name:
bone marrow stromal cells
Platform:
GPL18460
Series:
GSE139073
Download data
Sample
Accession:
GSM4128711
ID:
304128711
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSE139073[Accession]|query=1|qty=2|blobid=MCID_66543d9d6c053549899fabd4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center