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Items: 8

1.

Integrin αEβ7+ T cells direct intestinal stem cell fate decision via adhesive signaling

(Submitter supplied) Intestinal stem cells (ISCs) maintain gut homeostasis by differentiating into different epithelial cell types, which is precisely regulated by a niche of accessory cell types. In the niche, lymphocytes may interact with stem and transient amplifying (TA) cells in the intestinal crypts. However, it is unknown whether and how the lymphocyte- stem/TA cell contacts affect ISC differentiation. Here we discover and mechanistically dissect the role of T cell-stem/TA cell contacts in ISC fate decision. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
6 Samples
Download data: MTX, TSV
Series
Accession:
GSE135316
ID:
200135316
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

Itgb7 KO-3

Organism:
Mus musculus
Source name:
small intestine
Platform:
GPL21273
Series:
GSE135316
Download data: MTX, TSV
Sample
Accession:
GSM4005173
ID:
304005173
4.

Itgb7 KO-2

Organism:
Mus musculus
Source name:
small intestine
Platform:
GPL21273
Series:
GSE135316
Download data: MTX, TSV
Sample
Accession:
GSM4005172
ID:
304005172
5.

Itgb7 KO-1

Organism:
Mus musculus
Source name:
small intestine
Platform:
GPL21273
Series:
GSE135316
Download data: MTX, TSV
Sample
Accession:
GSM4005171
ID:
304005171
6.

WT-3

Organism:
Mus musculus
Source name:
small intestine
Platform:
GPL21273
Series:
GSE135316
Download data: MTX, TSV
Sample
Accession:
GSM4005170
ID:
304005170
7.

WT-2

Organism:
Mus musculus
Source name:
small intestine
Platform:
GPL21273
Series:
GSE135316
Download data: MTX, TSV
Sample
Accession:
GSM4005169
ID:
304005169
8.

WT-1

Organism:
Mus musculus
Source name:
small intestine
Platform:
GPL21273
Series:
GSE135316
Download data: MTX, TSV
Sample
Accession:
GSM4005168
ID:
304005168
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Supplemental Content

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