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Items: 8

1.

The microRNA miR-22 represses T helper 17 cell pathogenicity by targeting PTEN-regulated pathways

(Submitter supplied) Multiple sclerosis is a chronic autoimmune disease driven by pathogenic Th17 cells. Here, we dissected the role of miR-22 in pathogenic Th17 cells by autoantigen-specific disease models. We first showed that miR-22 was upregulated in peripheral lymphoid organs and spinal cords of mice developed autoimmune encephalomyelitis. Although miR-22 was upregulated in multiple helper T cell subsets, it was dispensable for T helper cell differentiation in vitro. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
6 Samples
Download data: TXT
Series
Accession:
GSE134895
ID:
200134895
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

Th17(23)_Control RNA-seq rep3

Organism:
Mus musculus
Source name:
TH17(23) cells
Platform:
GPL21273
Series:
GSE134895
Download data: TXT
Sample
Accession:
GSM3976575
ID:
303976575
4.

Th17(23)_Control RNA-seq rep2

Organism:
Mus musculus
Source name:
TH17(23) cells
Platform:
GPL21273
Series:
GSE134895
Download data: TXT
Sample
Accession:
GSM3976574
ID:
303976574
5.

Th17(23)_Control RNA-seq rep1

Organism:
Mus musculus
Source name:
TH17(23) cells
Platform:
GPL21273
Series:
GSE134895
Download data: TXT
Sample
Accession:
GSM3976573
ID:
303976573
6.

Th17(23)_miR-22-/- RNA-seq rep3

Organism:
Mus musculus
Source name:
TH17(23) cells
Platform:
GPL21273
Series:
GSE134895
Download data: TXT
Sample
Accession:
GSM3976572
ID:
303976572
7.

Th17(23)_miR-22-/- RNA-seq rep2

Organism:
Mus musculus
Source name:
TH17(23) cells
Platform:
GPL21273
Series:
GSE134895
Download data: TXT
Sample
Accession:
GSM3976571
ID:
303976571
8.

Th17(23)_miR-22-/- RNA-seq rep1

Organism:
Mus musculus
Source name:
TH17(23) cells
Platform:
GPL21273
Series:
GSE134895
Download data: TXT
Sample
Accession:
GSM3976570
ID:
303976570
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Supplemental Content

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