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Items: 4

1.

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance [CHIP-seq]

(Submitter supplied) In this study, we examined the role of the transcriptional regulator EGR2 in CD8+ T cell exhaustion during chronic viral infection. Flow cytometric and RNAseq analysis indicated that EGR2 deficient CD8+ T cells had a block in differentiation and failed to undergo terminal exhaustion. To examine the direct gene targets of EGR2 during exhaustion, we conducted ChIPseq analysis on enriched bulk splenic CD8+ T cells isolated at day 20 post-infection with chronic LCMV-Cl13 from C57BL/6J mice. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
2 Samples
Download data: NARROWPEAK
Series
Accession:
GSE134708
ID:
200134708

SRA Run Selector

2.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10171 Series
293973 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

3.

T cell Input control

Organism:
Mus musculus
Source name:
T cells
Platform:
GPL19057
Series:
GSE134708 GSE134710
Download data
Sample
Accession:
GSM3963951
ID:
303963951

SRA Run Selector

4.

T cell EGR2 ChIP

Organism:
Mus musculus
Source name:
T cells
Platform:
GPL19057
Series:
GSE134708 GSE134710
Download data: NARROWPEAK
Sample
Accession:
GSM3963950
ID:
303963950

SRA Run Selector

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db=gds|term=GSE134708[Accession]|query=1|qty=2|blobid=MCID_6706ea91c150633680526c47|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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