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Items: 6

1.

TOPORS, a tumor suppressor protein, maintains higher-order chromatin organization in mouse hepatocytes [RNA-seq]

(Submitter supplied) Within mammalian nuclear space, chromosomes are hierarchically folded into active (A) and inactive (B) compartments composed of topologically associating domains (TADs). Genomic regions interact with nuclear lamina, termed lamina-associated domains (LADs), associated with transcriptional repression. However, the molecular mechanisms underlying these 3D chromatin architectures remain undeciphered. Here, we demonstrate the role of a potential tumor suppressor, TOP1 Binding Arginine/Serine Rich Protein (TOPORS), in genome organization. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
4 Samples
Download data: TXT
Series
Accession:
GSE134623
ID:
200134623
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

RNA-seq_shTopors-2

Organism:
Mus musculus
Source name:
shTopors
Platform:
GPL21273
Series:
GSE134623 GSE134624
Download data
Sample
Accession:
GSM3959440
ID:
303959440
4.

RNA-seq_shTopors-1

Organism:
Mus musculus
Source name:
shTopors
Platform:
GPL21273
Series:
GSE134623 GSE134624
Download data
Sample
Accession:
GSM3959439
ID:
303959439
5.

RNA-seq_shCtrl-2

Organism:
Mus musculus
Source name:
shCtrl
Platform:
GPL21273
Series:
GSE134623 GSE134624
Download data
Sample
Accession:
GSM3959438
ID:
303959438
6.

RNA-seq_shCtrl-1

Organism:
Mus musculus
Source name:
shCtrl
Platform:
GPL21273
Series:
GSE134623 GSE134624
Download data
Sample
Accession:
GSM3959437
ID:
303959437
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Supplemental Content

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