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Items: 1 to 20 of 103

1.

Mutant Kras co-opts a progenitor-derived enhancer network to initiate pancreatic tumorigenesis [RNA-seq]

(Submitter supplied) Oncogenes are highly specific in the cells they can transform, although the molecular basis for this is poorly understood. Inflammation often promotes tumorigenesis, and in the pancreas it promotes cellular plasticity and accelerates Kras-driven neoplasia. We demonstrate that plasticity is coupled to the emergence of transient progenitor cells that are readily transformed by KrasG12D. The progenitor state is linked to coordinate upregulation of proliferation genes through chromatin opening at nearby lineage-specific enhancers. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
101 Samples
Download data: TXT
Series
Accession:
GSE134235
ID:
200134235
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

TAM_induced_D21_wt_R1-3_RNA-seq [new_D21_WT_m_pos_1948_3]

Organism:
Mus musculus
Source name:
normal pancreas(recovery)
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4452681
ID:
304452681
4.

TAM_induced_D21_wt_R1-2_RNA-seq [new_D21_WT_m_pos_1948_2]

Organism:
Mus musculus
Source name:
normal pancreas(recovery)
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4452680
ID:
304452680
5.

TAM_induced_D21_wt_R1-1_RNA-seq [new_D21_WT_m_pos_1948_1]

Organism:
Mus musculus
Source name:
normal pancreas(recovery)
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4452679
ID:
304452679
6.

TAM_induced_Tumor_R2-3_RNA-seq [new_Tumor_Kras_881-T3]

Organism:
Mus musculus
Source name:
KrasG12D,KO_Cdkn2a maintained Tumor
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445199
ID:
304445199
7.

TAM_induced_Tumor_R2-2_RNA-seq [new_Tumor_Kras_881-T2]

Organism:
Mus musculus
Source name:
KrasG12D,KO_Cdkn2a maintained Tumor
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445198
ID:
304445198
8.

TAM_induced_Tumor_R2-1_RNA-seq [new_Tumor_Kras_881-T1]

Organism:
Mus musculus
Source name:
KrasG12D,KO_Cdkn2a maintained Tumor
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445197
ID:
304445197
9.

TAM_induced_Tumor_R1-3_RNA-seq [new_Tumor_Kras_1991-3]

Organism:
Mus musculus
Source name:
KrasG12D,KO_Cdkn2a maintained Tumor
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445196
ID:
304445196
10.

TAM_induced_Tumor_R1-2_RNA-seq [new_Tumor_Kras_1991-2]

Organism:
Mus musculus
Source name:
KrasG12D,KO_Cdkn2a maintained Tumor
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445195
ID:
304445195
11.

TAM_induced_Tumor_R1-1_RNA-seq [new_Tumor_Kras_1991-1]

Organism:
Mus musculus
Source name:
KrasG12D,KO_Cdkn2a maintained Tumor
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445194
ID:
304445194
12.

TAM_induced_D7_KrasG12D_R2-3_RNA-seq [new_D7_Kras_m_pos_1961-3]

Organism:
Mus musculus
Source name:
Kras maintained ADM and panIN
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445193
ID:
304445193
13.

TAM_induced_D7_KrasG12D_R2-2_RNA-seq [new_D7_Kras_m_pos_1961-2]

Organism:
Mus musculus
Source name:
Kras maintained ADM and panIN
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445192
ID:
304445192
14.

TAM_induced_D7_KrasG12D_R2-1_RNA-seq [new_D7_Kras_m_pos_1961-1]

Organism:
Mus musculus
Source name:
Kras maintained ADM and panIN
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445191
ID:
304445191
15.

TAM_induced_D7_KrasG12D_R1-3_RNA-seq [new_D7_Kras_m_pos_1973-3]

Organism:
Mus musculus
Source name:
Kras maintained ADM and panIN
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445190
ID:
304445190
16.

TAM_induced_D7_KrasG12D_R1-2_RNA-seq [new_D7_Kras_m_pos_1973-2]

Organism:
Mus musculus
Source name:
Kras maintained ADM and panIN
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445189
ID:
304445189
17.

TAM_induced_D7_KrasG12D_R1-1_RNA-seq [new_D7_Kras_m_pos_1973-1]

Organism:
Mus musculus
Source name:
Kras maintained ADM and panIN
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445188
ID:
304445188
18.

TAM_induced_D0_KrasG12D_R1-3_RNA-seq [new_D0_Kras_m_pos_681-3]

Organism:
Mus musculus
Source name:
Kras induced in normal pancreas
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445187
ID:
304445187
19.

TAM_induced_D0_KrasG12D_R1-2_RNA-seq [new_D0_Kras_m_pos_681-2]

Organism:
Mus musculus
Source name:
Kras induced in normal pancreas
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445186
ID:
304445186
20.

TAM_induced_D0_KrasG12D_R1-1_RNA-seq [new_D0_Kras_m_pos_681-1]

Organism:
Mus musculus
Source name:
Kras induced in normal pancreas
Platform:
GPL21273
Series:
GSE134235 GSE134236
Download data
Sample
Accession:
GSM4445185
ID:
304445185
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