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Items: 5

1.

In vitro restoration of Friedreich's Ataxia defect with novel Cas9-edited hiPSC-derived Dorsal Root Ganglion-like Organoids (DRGOs) and Microfluidic System

(Submitter supplied) Friedreich's ataxia (FRDA) is an autosomal-recessive neurodegenerative and cardiac disorder which occurs when transcription of the frataxin (FXN) gene is silenced due to the expansion of GAA·TTC repeats in intron 1 of the same gene, leading loss of the essential mitochondrial protein frataxin with several impairment in iron metabolism and respiration, primarily affects the sensory DRG neurons. A major limitation in the study of FRDA is the lack of robust animal and cellular models. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
3 Samples
Download data: TAB
2.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
3.

DRGO-CTRL-3

Organism:
Homo sapiens
Source name:
iPSC-derived
Platform:
GPL21290
Series:
GSE133755
Download data: TAB
Sample
Accession:
GSM3926663
ID:
303926663
4.

DRGO-CTRL-2

Organism:
Homo sapiens
Source name:
iPSC-derived
Platform:
GPL21290
Series:
GSE133755
Download data: TAB
Sample
Accession:
GSM3926662
ID:
303926662
5.

DRGO-CTRL-1

Organism:
Homo sapiens
Source name:
iPSC-derived
Platform:
GPL21290
Series:
GSE133755
Download data: TAB
Sample
Accession:
GSM3926661
ID:
303926661
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Supplemental Content

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