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Items: 8

1.

ATAC-Seq analysis of Mouse Embryonic Fibroblasts (MEFs) to understand the role of β-actin in regulating chromatin states

(Submitter supplied) β-actin is a crucial component of several chromatin remodeling complexes which control chromatin structure and accessibility. The mammalian Brahma-associated factor (BAF) is one such complex that plays essential roles in development and differentiation by regulating the chromatin state of critical genes and opposing the repressive activity of polycomb repressive complexes. While previous work has shown that β-actin loss can lead to extensive changes in gene expression and heterochromatin organization, it is not known if changes in β-actin levels can directly influence chromatin remodeling activities of BAF and polycomb proteins. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
6 Samples
Download data: BW
Series
Accession:
GSE133196
ID:
200133196
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Wild type MEFs [WT_2]

Organism:
Mus musculus
Source name:
connective tissue - MEFs
Platform:
GPL24247
Series:
GSE133196
Download data: BW
Sample
Accession:
GSM3901940
ID:
303901940
4.

Wild type MEFs [WT_1]

Organism:
Mus musculus
Source name:
connective tissue - MEFs
Platform:
GPL24247
Series:
GSE133196
Download data: BW
Sample
Accession:
GSM3901939
ID:
303901939
5.

β-actin knockout MEFs [KO_2]

Organism:
Mus musculus
Source name:
connective tissue - MEFs
Platform:
GPL24247
Series:
GSE133196
Download data: BW
Sample
Accession:
GSM3901938
ID:
303901938
6.

β-actin knockout MEFs [KO_1]

Organism:
Mus musculus
Source name:
connective tissue - MEFs
Platform:
GPL24247
Series:
GSE133196
Download data: BW
Sample
Accession:
GSM3901937
ID:
303901937
7.

β-actin heterozygous MEFs [HET_2]

Organism:
Mus musculus
Source name:
connective tissue - MEFs
Platform:
GPL24247
Series:
GSE133196
Download data: BW
Sample
Accession:
GSM3901930
ID:
303901930
8.

β-actin heterozygous MEFs [HET_1]

Organism:
Mus musculus
Source name:
connective tissue - MEFs
Platform:
GPL24247
Series:
GSE133196
Download data: BW
Sample
Accession:
GSM3901929
ID:
303901929
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Supplemental Content

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