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Items: 7

1.

Identification of a T follicular helper subset that drives anaphylactic IgE

(Submitter supplied) We report a rare population of IL-13-producing Tfh cells that were present with high-affinity IgE to allergens. These “Tfh13” cells have an unusual cytokine profile (IL-13hiIL-4hiIL-5hiIL-21lo), co-express BCL6 and GATA3 and were required for production of high- but not low-affinity IgE and accordingly, allergen-induced anaphylaxis.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL21103
4 Samples
Download data: CSV, MTX, TSV
Series
Accession:
GSE132798
ID:
200132798
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
4.

Tfhs hashtag library

Organism:
Mus musculus
Source name:
Sorted Tfh cells (TCRβ+ CD4+ CD44+ PD-1+ CXCR5+)
Platform:
GPL21103
Series:
GSE132798
Download data: CSV
Sample
Accession:
GSM3892345
ID:
303892345
5.

Tfhs gene expression library

Organism:
Mus musculus
Source name:
Sorted Tfh cells (TCRβ+ CD4+ CD44+ PD-1+ CXCR5+)
Platform:
GPL21103
Series:
GSE132798
Download data: MTX, TSV
Sample
Accession:
GSM3892344
ID:
303892344
6.

IL-4+ hashtag library

Organism:
Mus musculus
Source name:
Sorted IL-4 4GET+ Activated CD4 T cells
Platform:
GPL24247
Series:
GSE132798
Download data: MTX, TSV
Sample
Accession:
GSM3892347
ID:
303892347
7.

IL-4+ gene expression library

Organism:
Mus musculus
Source name:
Sorted IL-4 4GET+ Activated CD4 T cells
Platform:
GPL24247
Series:
GSE132798
Download data: MTX, TSV
Sample
Accession:
GSM3892346
ID:
303892346
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Supplemental Content

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