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Items: 14

1.

Gene regulation by restoration of KMT2C in human colorectal cancer cells HCT116 and RKO

(Submitter supplied) The histone 3 lysine 4 (H3K4) monomethylase KMT2C is mutated across several cancer types, however the effects of mutations on epigenome organization, gene expression and cell growth are not clear. To study effects of KMT2C expression in CRC cells we restored one allele to wild type KMT2C in the two CRC cell lines RKO and HCT116, which both are homozygous KMT2C c.8390delA mutant, by gene editing. RNA sequencing was performed to profile gene expression when KMT2C was restored in RKO and HCT116 cells.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17303
12 Samples
Download data: TXT
2.

Ion Torrent Proton (Homo sapiens)

Platform
Accession:
GPL17303
ID:
100017303
3.

RKO KMT2C KI2_2

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782973
ID:
303782973
4.

RKO KMT2C KI2_1

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782972
ID:
303782972
5.

RKO KMT2C KI1

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782971
ID:
303782971
6.

RKO_3

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782970
ID:
303782970
7.

RKO_2

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782969
ID:
303782969
8.

RKO_1

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782968
ID:
303782968
9.

HCT116 KMT2C KI3

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782967
ID:
303782967
10.

HCT116 KMT2C KI2

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782966
ID:
303782966
11.

HCT116 KMT2C KI1

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782965
ID:
303782965
12.

HCT116_3

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782964
ID:
303782964
13.

HCT116_2

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782963
ID:
303782963
14.

HCT116_1

Organism:
Homo sapiens
Source name:
Cell culture
Platform:
GPL17303
Series:
GSE131507
Download data: TXT
Sample
Accession:
GSM3782962
ID:
303782962
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Supplemental Content

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