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Items: 6

1.

Nuclear speckles as a key regulator for the 3D genome organization [HiC]

(Submitter supplied) The nuclei of eukaryotes contain various higher-order chromatin architectures and nuclear bodies (NBs), which are critical for proper nuclear functions. By using mouse hepatocytes as the model, we knocked-down SRRM2, a core protein component scaffolding NSs, and performed Hi-C experiments to examine genome-wide chromatin interactions. We found that Srrm2 depletion disrupted the NSs and changes expression of about 1,000 genes. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL21273
4 Samples
Download data: HIC
Series
Accession:
GSE131463
ID:
200131463
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

Aml12_KD_rep2

Organism:
Mus musculus
Source name:
AML12
Platform:
GPL21273
Series:
GSE131463 GSE131466
Download data: HIC
Sample
Accession:
GSM3780960
ID:
303780960
4.

Aml12_KD_rep1

Organism:
Mus musculus
Source name:
AML12
Platform:
GPL21273
Series:
GSE131463 GSE131466
Download data: HIC
Sample
Accession:
GSM3780959
ID:
303780959
5.

Aml12_Ctrl_rep2

Organism:
Mus musculus
Source name:
AML12
Platform:
GPL21273
Series:
GSE131463 GSE131466
Download data: HIC
Sample
Accession:
GSM3780958
ID:
303780958
6.

Aml12_Ctrl_rep1

Organism:
Mus musculus
Source name:
AML12
Platform:
GPL21273
Series:
GSE131463 GSE131466
Download data: HIC
Sample
Accession:
GSM3780957
ID:
303780957
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Supplemental Content

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