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Items: 14

1.

Stereotyped transcriptomic transformation of somatosensory neurons in response to injury

(Submitter supplied) In mice, spared nerve injury replicates symptoms of human neuropathic pain and induces upregulation of many genes in somatosensory neurons. Here we used single cell transcriptomics to probe the effects of partial infraorbital transection of the trigeminal nerve at the cellular level. Uninjured neurons were unaffected by transection of major nerve branches, segregating into many different classes. In marked contrast, axotomy rapidly transformed damaged neurons into just two new and closely-related classes where almost all original identity was lost. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL16417 GPL19057
11 Samples
Download data: CSV
Series
Accession:
GSE131272
ID:
200131272
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

Illumina MiSeq (Mus musculus)

Platform
Accession:
GPL16417
ID:
100016417
4.

WT_TG_3_DropSeq

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL16417
Series:
GSE131272
Download data
Sample
Accession:
GSM3768366
ID:
303768366
5.

WT_TG_2_DropSeq

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL16417
Series:
GSE131272
Download data
Sample
Accession:
GSM3768365
ID:
303768365
6.

WT_TG_1_DropSeq

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL16417
Series:
GSE131272
Download data
Sample
Accession:
GSM3768364
ID:
303768364
7.

facial injury

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768374
ID:
303768374
8.

itch_lesions

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768373
ID:
303768373
9.

SNI_75dpi

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768372
ID:
303768372
10.

SNI_21dpi

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768371
ID:
303768371
11.

SNI_7dpi

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768370
ID:
303768370
12.

SNI_2dpi

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768369
ID:
303768369
13.

WT_TG_5_10x

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768368
ID:
303768368
14.

WT_TG_4_DropSeq

Organism:
Mus musculus
Source name:
trigeminal nuclei
Platform:
GPL19057
Series:
GSE131272
Download data
Sample
Accession:
GSM3768367
ID:
303768367
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Supplemental Content

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