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Items: 4

1.

SETDB1 safeguards genome stability against necroptosis and bowel inflammation (ChIP-seq)

(Submitter supplied) The aetiology of bowel inflammatory disease (IBD) is a multifactorial interplay between heredity and environment1-3. Here we report SETDB1, a histone methyltransferase (HMTs) for histone H3 lysine 9 trimethylation (H3K9me3) whose deficiency participates in the pathogenesis of IBD. We found that SETDB1 level decreased in IBD patients and that mice with reduced SETDB1 in intestinal stem cells (ISCs) developed spontaneous terminal ileitis and colitis. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21273
2 Samples
Download data: TXT
Series
Accession:
GSE129173
ID:
200129173
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

ISC_input

Organism:
Mus musculus
Source name:
intestines
Platform:
GPL21273
Series:
GSE129173 GSE129174
Download data
Sample
Accession:
GSM3701977
ID:
303701977
4.

ISC_ChIP_H3K9me3

Organism:
Mus musculus
Source name:
intestines
Platform:
GPL21273
Series:
GSE129173 GSE129174
Download data: TXT
Sample
Accession:
GSM3701976
ID:
303701976
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Supplemental Content

db=gds|term=GSE129173[Accession]|query=1|qty=2|blobid=MCID_664f399dd01e38019c98e900|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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