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Items: 10

1.

Loss of DKM6A confers drug resistance in acute myeloid leukemia (ChIP-seq of AML cell lines MM-1 and MM-6)

(Submitter supplied) Acute myeloid leukemia (AML) is an aggressive hematologic neoplasm resulting from the malignant transformation of myeloid progenitors. Despite intensive chemotherapy leading to initial treatment responses, relapse caused by intrinsic or acquired drug resistance represents a major challenge. Here, we report that histone 3 lysine 27 demethylase KDM6A (UTX) is targeted by inactivating mutations and mutation-independent regulation in relapsed AML. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18460
8 Samples
Download data: BIGWIG
Series
Accession:
GSE128259
ID:
200128259
2.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
3.

GS701 MM6 H3K27me3 ChIPseq rep2

Organism:
Homo sapiens
Source name:
AML cell line MM6
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669490
ID:
303669490
4.

GS216 MM6 H3K27me3 ChIPseq rep1

Organism:
Homo sapiens
Source name:
AML cell line MM6
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669489
ID:
303669489
5.

GS700 MM1 H3K27me3 ChIPseq rep2

Organism:
Homo sapiens
Source name:
AML cell line MM1
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669488
ID:
303669488
6.

GS215 MM1 H3K27me3 ChIPseq rep1

Organism:
Homo sapiens
Source name:
AML cell line MM1
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669487
ID:
303669487
7.

GS656 MM6 H3K27ac ChIPseq rep2

Organism:
Homo sapiens
Source name:
AML cell line MM6
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669486
ID:
303669486
8.

GS210 MM6 H3K27ac ChIPseq rep1

Organism:
Homo sapiens
Source name:
AML cell line MM6
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669485
ID:
303669485
9.

GS654 MM1 H3K27ac ChIPseq rep2

Organism:
Homo sapiens
Source name:
AML cell line MM1
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669484
ID:
303669484
10.

GS187 MM1 H3K27ac ChIPseq rep1

Organism:
Homo sapiens
Source name:
AML cell line MM1
Platform:
GPL18460
Series:
GSE128259 GSE128262
Download data: BIGWIG
Sample
Accession:
GSM3669483
ID:
303669483
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Supplemental Content

db=gds|term=GSE128259[Accession]|query=1|qty=2|blobid=MCID_664b55f28626ff46af844583|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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