U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 11

1.

Maintenance of nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis

(Submitter supplied) CBX4, a component of polycomb repressive complex 1 (PRC1), plays important roles in the maintenance of cell identity and organ development through epigenetic silencing. However, whether CBX4 regulates the homeostasis of human stem cells remains unclear. Here, we demonstrate that CBX4 counteracts human mesenchymal stem cell (hMSC) aging via the maintenance of nucleolar homeostasis. CBX4 protein is decreased in aged hMSCs, and targeted CBX4 knockout in young hMSCs results in destabilized nucleolar heterochromatin, increased ribosome biogenesis and protein translation, and accelerated cellular senescence. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
9 Samples
Download data: TSV
Series
Accession:
GSE125320
ID:
200125320
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

OA model_Lentiviruses expressing CBX4 rep3

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568923
ID:
303568923
4.

OA model_Lentiviruses expressing CBX4 rep2

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568922
ID:
303568922
5.

OA model_Lentiviruses expressing CBX4 rep1

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568921
ID:
303568921
6.

OA model_Lentiviruses expressing Luc rep3

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568920
ID:
303568920
7.

OA model_Lentiviruses expressing Luc rep2

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568919
ID:
303568919
8.

OA model_Lentiviruses expressing Luc rep1

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568918
ID:
303568918
9.

OA model_Non surgery rep3

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568917
ID:
303568917
10.

OA model_Non surgery rep2

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568916
ID:
303568916
11.

OA model_Non surgery rep1

Organism:
Mus musculus
Source name:
knee joints
Platform:
GPL21273
Series:
GSE125320
Download data: TSV
Sample
Accession:
GSM3568915
ID:
303568915
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSE125320[Accession]|query=1|qty=2|blobid=MCID_6655f003e795547e5fc7e888|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center