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Items: 6

1.

Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissue-of-origin

(Submitter supplied) Three-dimensional chromatin organization varies across different cell types and is essential for gene regulation. However, current technologies are unable to assess in vivo genome-wide chromatin organization non-invasively. Here, we showed that long-range correlations in the fragment length of cell-free DNA (cfDNA) estimated from whole-genome sequencing recapitulate three-dimensional chromatin organization. more...
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL20795 GPL24676
3 Samples
Download data: HIC
Series
Accession:
GSE124974
ID:
200124974
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

HiSeq X Ten (Homo sapiens)

Platform
Accession:
GPL20795
ID:
100020795
4.

HiC_wbc_rep2

Organism:
Homo sapiens
Source name:
white blood cells
Platform:
GPL20795
Series:
GSE124974
Download data: HIC
Sample
Accession:
GSM3560408
ID:
303560408
5.

HiC_wbc_rep1

Organism:
Homo sapiens
Source name:
white blood cells
Platform:
GPL20795
Series:
GSE124974
Download data: HIC
Sample
Accession:
GSM3560407
ID:
303560407
6.

HiC_neutrophil

Organism:
Homo sapiens
Source name:
neutrophils (from Astarte Biologics Inc)
Platform:
GPL24676
Series:
GSE124974
Download data: HIC
Sample
Accession:
GSM3560409
ID:
303560409
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Supplemental Content

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