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Items: 14

1.

Global effects of SUPT4H1 RNAi on gene expression of HEK293 cells

(Submitter supplied) SUPT4H1 is a transcription elongation factor comprising part of the RNA polymerase II complex. Recent studies propose a selective role for SUPT4H1 in transcription of repeat-containing transcripts; the translated products of which being a hallmark of neurodegeneration in disorders such as Huntington’s Disease and C9orf72-amyotrophic lateral sclerosis. To investigate the potential of SUPT4H1 as a therapeutic target in repeat-associated neurodegeneration, we depleted SUPT4H1 by RNA interference in order to mimic pharmacological loss of function. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
12 Samples
Download data: TAB
Series
Accession:
GSE116267
ID:
200116267
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

S912: DARP-EGFP line 2, SUPT4H1 siRNAs, replicate 2

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223419
ID:
303223419
4.

S832: DARP-EGFP line 2, SUPT4H1 siRNAs, replicate 1

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223418
ID:
303223418
5.

S783: DARP-EGFP line 1, scrambled siRNAs, replicate 2

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223417
ID:
303223417
6.

S623: EGFP line, SUPT4H1 siRNAs, replicate 2

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223416
ID:
303223416
7.

S622: DARP-EGFP line 2, scrambled siRNAs, replicate 2

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223415
ID:
303223415
8.

S487: DARP-EGFP line 1, SUPT4H1 siRNAs, replicate 2

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223414
ID:
303223414
9.

S458: EGFP line, scrambled siRNAs, replicate 2

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223413
ID:
303223413
10.

S420: EGFP line, SUPT4H1 siRNAs, replicate 1

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223412
ID:
303223412
11.

S320: DARP-EGFP line 1, scrambled siRNAs, replicate 1

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223411
ID:
303223411
12.

S255: EGFP line, scrambled siRNAs, replicate 1

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223410
ID:
303223410
13.

S190: DARP-EGFP line 1, SUPT4H1 siRNAs, replicate 1

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223409
ID:
303223409
14.

S168: DARP-EGFP line 2, scrambled siRNAs, replicate 1

Organism:
Homo sapiens
Source name:
Human embryonic kidney
Platform:
GPL24676
Series:
GSE116267
Download data
Sample
Accession:
GSM3223408
ID:
303223408
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Supplemental Content

db=gds|term=GSE116267[Accession]|query=1|qty=2|blobid=MCID_65dbcaafa642ff6770b07425|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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