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Items: 1 to 20 of 61

1.

SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development [ChIP-seq]

(Submitter supplied) The oocyte epigenome plays critical roles in mammalian gametogenesis and embryogenesis. Yet, how it is established remains elusive. Here, we report that histone-lysine N-methyltransferase SETD2, an H3K36me3 methyltransferase, is a crucial regulator of the mouse oocyte epigenome. Deficiency in Setd2 leads to extensive alterations of the oocyte epigenome, including the loss of H3K36me3, failure in establishing the correct DNA methylome, invasion of H3K4me3 and H3K27me3 into former H3K36me3 territories and aberrant acquisition of H3K4me3 at imprinting control regions instead of DNA methylation. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21273 GPL17021
58 Samples
Download data: BED
Series
Accession:
GSE112834
ID:
200112834
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

ChIP_FGO_Setd2_Con_H3K27ac_rep1

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL17021
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM4130751
ID:
304130751
5.

ChIP_FGO_Setd2_KO_H3K27ac_rep2

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM4130754
ID:
304130754
6.

ChIP_FGO_Setd2_KO_H3K27ac_rep1

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM4130753
ID:
304130753
7.

ChIP_FGO_Setd2_Con_H3K27ac_rep2

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM4130752
ID:
304130752
8.

ChIP_FGO_Setd2_KO_H3K4me3_rep3

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL17021
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3084647
ID:
303084647
9.

ChIP_FGO_Setd2_Con_H3K4me3_rep3

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL17021
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3084644
ID:
303084644
10.

ChIP_FGO_Dnmt3l_KO_H3K27me3_rep1

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL17021
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3084640
ID:
303084640
11.

ChIP_FGO_Setd2_Con_H3K27me3_rep2

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494262
ID:
303494262
12.

ChIP_ST_8C_Setd2_KO_H3K27me3

Organism:
Mus musculus
Source name:
embryo
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494261
ID:
303494261
13.

ChIP_ST_8C_Setd2_KO_H3K4me3

Organism:
Mus musculus
Source name:
embryo
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494260
ID:
303494260
14.

ChIP_ST_Early2C_Setd2_KO_H3K27me3

Organism:
Mus musculus
Source name:
embryo
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494259
ID:
303494259
15.

ChIP_ST_Early2C_Setd2_KO_H3K4me3

Organism:
Mus musculus
Source name:
embryo
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494258
ID:
303494258
16.

ChIP_GO_P7_Setd2_KO_H3K27me3

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494257
ID:
303494257
17.

ChIP_GO_P7_Setd2_KO_H3K4me3

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494256
ID:
303494256
18.

ChIP_FGO_Dnmt3l_KO_H3K36me3_rep2

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494255
ID:
303494255
19.

ChIP_FGO_Dnmt3l_Con_H3K27me3_rep2

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494254
ID:
303494254
20.

ChIP_FGO_Dnmt3l_Con_H3K27me3_rep1

Organism:
Mus musculus
Source name:
oocyte
Platform:
GPL21273
Series:
GSE112834 GSE112835
Download data
Sample
Accession:
GSM3494253
ID:
303494253
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Supplemental Content

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