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Items: 13

1.

The Effect of TLR2 Activation on Transcriptome of IFN-induced Microglia

(Submitter supplied) In murine glioma models, TLR2 is selectively upregulated in glioma-associated microglia. We found that TLR2 activation led to down-regulation of MHC-II in microglia. Therefore, we examined the effect of TLR2 activation on IFN-gamma-induced microglial transcriptome by in vitro culture of murine adult microglia. In the study, we confirmed that TLR2 activation led to Ciita shutdown and inhibition of MHC-II related genes, which also revealed the role of TLR2 in inducing APC disability and tumor immune escape. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
11 Samples
Download data: TXT
Series
Accession:
GSE109297
ID:
200109297
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

Pam3CSK4 IFN-g rep3

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936677
ID:
302936677
4.

Pam3CSK4 IFN-g rep2

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936676
ID:
302936676
5.

Pam3CSK4 IFN-g rep1

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936675
ID:
302936675
6.

IFN-g rep3

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936674
ID:
302936674
7.

IFN-g rep2

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936673
ID:
302936673
8.

IFN-g rep1

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936672
ID:
302936672
9.

Pam3CSK4 rep2

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936671
ID:
302936671
10.

Pam3CSK4 rep1

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936670
ID:
302936670
11.

Control rep3

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936669
ID:
302936669
12.

Control rep2

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936668
ID:
302936668
13.

Control rep1

Organism:
Mus musculus
Source name:
adult microglia
Platform:
GPL21273
Series:
GSE109297
Download data
Sample
Accession:
GSM2936667
ID:
302936667
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Supplemental Content

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