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Items: 7

1.

Functional Genomics Analysis of Islets from Recent and Longstanding T1D Reveals the Need for Distinct Approaches to Therapy

(Submitter supplied) Our current understanding of the pathogenesis of T1D arose in large part from studies using the non-obese diabetic (NOD) mouse model of type 1 diabetes (T1D). Of concern, therapeutic interventions shown to significantly dampen or even reverse disease in mouse models have not successfully translated into interventions in human T1D. The present study addresses this disconnect in research translation by directly analyzing human donor islets from individuals with T1D, aiming to provide insight into disease mechanisms and identify potential target pathways for therapeutic intervention. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
5 Samples
Download data: GTF
Series
Accession:
GSE102371
ID:
200102371
2.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
3.

islet preparation from short duration type 1 diabetes

Organism:
Homo sapiens
Source name:
islets of Langerhans
Platform:
GPL21290
Series:
GSE102371
Download data: GTF
Sample
Accession:
GSM2735601
ID:
302735601
4.

islet preparation from long duration type 1 diabetes

Organism:
Homo sapiens
Source name:
islets of Langerhans
Platform:
GPL21290
Series:
GSE102371
Download data: GTF
Sample
Accession:
GSM2735600
ID:
302735600
5.

islet preparation from normo-glycemic individual 3

Organism:
Homo sapiens
Source name:
islets of Langerhans
Platform:
GPL21290
Series:
GSE102371
Download data: GTF
Sample
Accession:
GSM2735599
ID:
302735599
6.

islet preparation from normo-glycemic individual 2

Organism:
Homo sapiens
Source name:
islets of Langerhans
Platform:
GPL21290
Series:
GSE102371
Download data: GTF
Sample
Accession:
GSM2735598
ID:
302735598
7.

islet preparation from normo-glycemic individual 1

Organism:
Homo sapiens
Source name:
islets of Langerhans
Platform:
GPL21290
Series:
GSE102371
Download data: GTF
Sample
Accession:
GSM2735597
ID:
302735597
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