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Items: 11

1.

Single Copy Loss of Tet1 disrupts neural stem cell differentiation and enhances GBM aggressiveness

(Submitter supplied) Glioblastoma (GBM) is a highly aggressive brain tumor, characterized by poorly differentiated cells that drive disease growth and relapse. In contrast to normal neural stem cells (NSCs) which show a highly orderly process of differentiation, GBM precursors exhibit differentiation failure. In order to identify new mechanisms involved in neuronal differentiation that may have bearing on understanding GBM, we performed an unbiased phenotypic screen, utilizing a library of mouse embryonic stem cell (mESC) clones carrying 1307 unique variable length haplodeletions (altogether covering 25% of the mouse genome). more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
9 Samples
Download data: TXT
Series
Accession:
GSE102136
ID:
200102136

Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
12133 Series
348663 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

TET1 homozygous loss of function mutant replicate 3

Organism:
Homo sapiens
Source name:
TET1 homozygous loss of function mutant, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728749
ID:
302728749

SRA Run Selector

4.

TET1 homozygous loss of function mutant replicate 2

Organism:
Homo sapiens
Source name:
TET1 homozygous loss of function mutant, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728748
ID:
302728748

SRA Run Selector

5.

TET1 homozygous loss of function mutant replicate 1

Organism:
Homo sapiens
Source name:
TET1 homozygous loss of function mutant, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728747
ID:
302728747

SRA Run Selector

6.

TET1 heterozygous loss of function mutant replicate 3

Organism:
Homo sapiens
Source name:
TET1 heterozygous loss of function mutant, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728746
ID:
302728746

SRA Run Selector

7.

TET1 heterozygous loss of function mutant replicate 2

Organism:
Homo sapiens
Source name:
TET1 heterozygous loss of function mutant, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728745
ID:
302728745

SRA Run Selector

8.

TET1 heterozygous loss of function mutant replicate 1

Organism:
Homo sapiens
Source name:
TET1 heterozygous loss of function mutant, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728744
ID:
302728744

SRA Run Selector

9.

WT control replicate 3

Organism:
Homo sapiens
Source name:
WT control, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728743
ID:
302728743

SRA Run Selector

10.

WT control replicate 2

Organism:
Homo sapiens
Source name:
WT control, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728742
ID:
302728742

SRA Run Selector

11.

WT control replicate 1

Organism:
Homo sapiens
Source name:
WT control, primary human glioblastoma culture
Platform:
GPL16791
Series:
GSE102136
Download data
Sample
Accession:
GSM2728741
ID:
302728741

SRA Run Selector

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db=gds|term=GSE102136[Accession]|query=1|qty=2|blobid=MCID_6701ed94d3e79154ac4c8fc9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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