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Items: 1 to 20 of 34

1.

HIV-1 infection of human monocyte-derived dendritic cells with and without the integrase inhibitor, Raltegravir (gene expression).

(Submitter supplied) Myeloid dendritic cells (DCs) have the innate capacity to sense pathogens and orchestrate immune responses. However, DCs do not mount efficient immune responses to HIV-1, due to potent restriction at the level of reverse transcription. Here, we uncover that when reverse transcription is allowed to proceed, DCs detect HIV-1 in distinct phases, before and after integration. Blocking integration suppressed, but did not abolish, activation of the transcription factor, IRF3, interferon responses, and DC maturation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17077
32 Samples
Download data: TXT
Series
Accession:
GSE100374
ID:
200100374
2.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...
Organism:
Homo sapiens
572 Series
1 Related Platform
9505 Samples
Download data
Platform
Accession:
GPL17077
ID:
100017077
3.

D187_HIV_RAL_40h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 40, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679733
ID:
302679733
4.

D186_HIV_RAL_40h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 40, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679732
ID:
302679732
5.

D187_HIV_RAL_32h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 32, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679731
ID:
302679731
6.

D186_HIV_RAL_32h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 32, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679730
ID:
302679730
7.

D187_HIV_RAL_28h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 28, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679729
ID:
302679729
8.

D186_HIV_RAL_28h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 28, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679728
ID:
302679728
9.

D187_HIV_RAL_24h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 24, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679727
ID:
302679727
10.

D186_HIV_RAL_24h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 24, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679726
ID:
302679726
11.

D187_HIV_RAL_20h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 20, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679725
ID:
302679725
12.

D186_HIV_RAL_20h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 20, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679724
ID:
302679724
13.

D187_HIV_RAL_16h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 16, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679723
ID:
302679723
14.

D186_HIV_RAL_16h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 16, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679722
ID:
302679722
15.

D187_HIV_RAL_8h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 8, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679721
ID:
302679721
16.

D186_HIV_RAL_8h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 8, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679720
ID:
302679720
17.

D187_VLP_mock_RAL

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells with mock infection in the presence of Vpx, time (hours): 40, drug: Raltegravir, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679719
ID:
302679719
18.

D186_VLP_mock_RAL

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells with mock infection in the presence of Vpx, time (hours): 40, drug: Raltegravir, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679718
ID:
302679718
19.

D187_HIV_40h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 40, drug: none, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679717
ID:
302679717
20.

D186_HIV_40h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 40, drug: none, donor: D186
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679716
ID:
302679716
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