GEO DataSets

(Submitter supplied) Histone H3 is assembled into nucleosomes during replication but is replaced by the H3.3 variant at sites of active transcription. Thus replacement levels provide a quantitative measure of histone turnover during transcriptional elongation and other active processes in dividing cells. Here we provide new insights into epigenetic regulation with the first genome-wide chromatin profile at 100-bp resolution, based on measurements of H3.3 levels throughout the Drosophila genome. more...

Organism:

Drosophila melanogaster

Type:

Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL3353 GPL3352 GPL3354

6 Samples

Download data: BEDGRAPH, GFF

(Submitter supplied) Cellular memory is maintained at the Drosophila homeotic gene clusters by cis-regulatory elements who mechanism of action is unknown. We have examined chromatin dynamics in the Drosophila genome by measuring histone turnover levels at high resolution. Surprisingly, homeotic gene clusters display characteristic histone turnover profiles with conspicuous peaks at boundaries of cis-regulatory domains superimposed over regions of very low turnover. more...

Organism:

Drosophila melanogaster

Type:

Genome binding/occupancy profiling by genome tiling array

4 related Platforms

11 Samples

Download data: BEDGRAPH, GFF

(Submitter supplied) Fly tiling array using NimbleGen platform (DesignID=2347), chip 1 of 3. FlyBase release 4.2. All of Chr 3R with isothermal oligos averaging 50bp. Dense tiling of Chr 2L proximal, Chr X proximal and distal, first part of Chr 4, and Bithorax complex (BXC1). Protocol: http://www.nimblegen.com/products/chip/index.html

Organism:

Drosophila melanogaster

2 Series

3 Samples

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