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Items: 20

1.

Extensive sex differences in depression-linked variants functionally assayed in mouse brain [Hippocampus II]

(Submitter supplied) Here, we selected >1000 variants from over 30 depression-associated loci using brain epigenomic data, and functionally assayed them using in vivo functional assays in the mouse brain to examine sex-by-genotype interactions. We identify extensive sex-by-allele effects in mature hippocampus, suggesting genetic risk and thus disease mechanisms may be distinct between the sexes. Unbiased informatics approaches indicated a role for nuclear hormone receptors, which was supported by . more...
Organism:
Adeno-associated virus 9; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL30885
38 Samples
Download data: TXT
Series
Accession:
GSE222184
ID:
200222184
2.

Extensive sex differences in depression-linked variants functionally assayed in mouse brain

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Adeno-associated virus 9; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL24247 GPL30885
69 Samples
Download data
Series
Accession:
GSE186348
ID:
200186348
3.

Extensive sex differences in depression-linked variants functionally assayed in mouse brain [P0&P10]

(Submitter supplied) Here, we selected >1000 variants from over 30 depression-associated loci using brain epigenomic data, and functionally assayed them using in vivo functional assays in the mouse brain to examine sex-by-genotype interactions. We identify extensive sex-by-allele effects in mature hippocampus, suggesting genetic risk and thus disease mechanisms may be distinct between the sexes. Unbiased informatics approaches indicated a role for nuclear hormone receptors, which was supported by . more...
Organism:
Adeno-associated virus 9; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL24247 GPL30885
44 Samples
Download data: TXT
Series
Accession:
GSE186347
ID:
200186347
4.

Extensive sex differences in depression-linked variants functionally assayed in mouse brain [Hippocampus]

(Submitter supplied) Here, we selected >1000 variants from over 30 depression-associated loci using brain epigenomic data, and functionally assayed them using in vivo functional assays in the mouse brain to examine sex-by-genotype interactions. We identify extensive sex-by-allele effects in mature hippocampus, suggesting genetic risk and thus disease mechanisms may be distinct between the sexes. Unbiased informatics approaches indicated a role for nuclear hormone receptors, which was supported by . more...
Organism:
Adeno-associated virus 9; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL24247 GPL30885
25 Samples
Download data: TXT
Series
Accession:
GSE186346
ID:
200186346
5.

Illumina NovaSeq 6000 (Adeno-associated virus 9)

Organism:
Adeno-associated virus 9
4 Series
15 Samples
Download data
Platform
Accession:
GPL30885
ID:
100030885
6.

AAV_Lysate6_Rep2

Organism:
Adeno-associated virus 9
Source name:
AAV_Lysate6
Platform:
GPL30885
Series:
GSE222184
Download data
Sample
Accession:
GSM6917363
ID:
306917363
7.

AAV_Lysate6_Rep1

Organism:
Adeno-associated virus 9
Source name:
AAV_Lysate6
Platform:
GPL30885
Series:
GSE222184
Download data
Sample
Accession:
GSM6917362
ID:
306917362
8.

AAV_Lyaste5_Rep2

Organism:
Adeno-associated virus 9
Source name:
AAV_Lysate5
Platform:
GPL30885
Series:
GSE222184
Download data
Sample
Accession:
GSM6917361
ID:
306917361
9.

AAV_Lyaste5_Rep1

Organism:
Adeno-associated virus 9
Source name:
AAV_Lysate5
Platform:
GPL30885
Series:
GSE222184
Download data
Sample
Accession:
GSM6917360
ID:
306917360
10.

AAV_seqprep2_techrep4

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186347 GSE186348
Download data
Sample
Accession:
GSM5645990
ID:
305645990
11.

AAV_seqprep1_techrep3

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186347 GSE186348
Download data
Sample
Accession:
GSM5645989
ID:
305645989
12.

AAV_seqprep2_techrep3

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186347 GSE186348
Download data
Sample
Accession:
GSM5645988
ID:
305645988
13.

AAV_seqprep1_techrep2

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186347 GSE186348
Download data
Sample
Accession:
GSM5645987
ID:
305645987
14.

AAV_seqprep2_techrep2

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186347 GSE186348
Download data
Sample
Accession:
GSM5645986
ID:
305645986
15.

AAV_seqprep1_techrep1

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186347 GSE186348
Download data
Sample
Accession:
GSM5645985
ID:
305645985
16.

AAV_seqprep2_techrep1

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186347 GSE186348
Download data
Sample
Accession:
GSM5645984
ID:
305645984
17.

AAV9_Lysate_TechRep4

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186346 GSE186348
Download data
Sample
Accession:
GSM5645925
ID:
305645925
18.

AAV9_Lysate_TechRep3

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186346 GSE186348
Download data
Sample
Accession:
GSM5645924
ID:
305645924
19.

AAV9_Lysate_TechRep2

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186346 GSE186348
Download data
Sample
Accession:
GSM5645923
ID:
305645923
20.

AAV9_Lysate_TechRep1

Organism:
Adeno-associated virus 9
Source name:
AAV9
Platform:
GPL30885
Series:
GSE186346 GSE186348
Download data
Sample
Accession:
GSM5645922
ID:
305645922
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