GEO DataSets

(Submitter supplied) Retinoblastoma is the most common intraocular cancer of infancy and childhood, with an incidence of one case per 15,000 - 20,000 live births. An early event in retinoblastoma genesis is a functional loss of both alleles of the RB1 gene. However, other genes are likely to be involved in the development of this cancer. In this study we sought to build a comprehensive molecular portrait of this cancer by performing transcriptomic, methylomic, as well as genomic profiling of primary retinoblastoma samples. more...

Organism:

Homo sapiens

Type:

Expression profiling by array; Genome variation profiling by SNP array; Methylation profiling by genome tiling array; Genome variation profiling by genome tiling array

7 related Platforms

312 Samples

Download data: CEL, CSV, IDAT, XLS, XLSX

(Submitter supplied) Retinoblastoma is the most common intraocular cancer of infancy and childhood, with an incidence of one case per 15,000 - 20,000 live births. An early event in retinoblastoma genesis is a functional loss of both alleles of the RB1 gene. However, other genes are likely to be involved in the development of this cancer. In this study we sought to build a comprehensive molecular portrait of this cancer by performing transcriptomic, methylomic, genomic profiling of primary retinoblastoma samples. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by genome tiling array

Platforms:

GPL18861 GPL29807

78 Samples

Download data: TXT

(Submitter supplied) The IntegraChipTM microarray was designed by the CIT-CGH consortium (Olivier Delattre Laboratory, Curie Institute, Paris; Charles Theillet Laboratory, CRLC Val d'Aurelle, Montpellier; Stanislas du Manoir Laboratory, IGBMC, Strasbourg) and the company IntegraGenTM (http://www.integragen.com). Bacterial artificial chromosome (BAC) clones were chosen to obtain a systematic coverage of the genome, and detailed coverage of regions containing genes previously implicated in carcinogenesis. more...

Organism:

Homo sapiens

2 Series

26 Samples

Download data