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1.

DRUID: A pipeline for reproducible transcriptome-wide measurements of mRNA stability

(Submitter supplied) We present DRUID (for Determination of Rates Using Intron Dynamics), a computational pipeline, for determining mRNA stability transcriptome-wide uses metabolic labeling and approach-to-equilibrium kinetics. Our pipeline uses endogenous introns to normalize time course data and yields more reproducible half-lives than other methods, even with datasets that were otherwise unusable. DRUID can handle datasets from a variety of organisms, spanning yeast to humans.
Organism:
Homo sapiens; Mus musculus; Saccharomyces cerevisiae; Caenorhabditis elegans; Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
4 related Platforms
66 Samples
Download data: CSV
Series
Accession:
GSE99517
ID:
200099517
2.

Illumina HiSeq 2500 (Homo sapiens; Saccharomyces cerevisiae)

Organism:
Saccharomyces cerevisiae; Homo sapiens
1 Series
26 Samples
Download data
Platform
Accession:
GPL23532
ID:
100023532
3.

Aman_2_24h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645431
ID:
302645431
4.

Aman_2_12h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645430
ID:
302645430
5.

Aman_2_8h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645429
ID:
302645429
6.

Aman_2_4h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645428
ID:
302645428
7.

Aman_2_2h_R1.fastq.gz

Organism:
Homo sapiens; Saccharomyces cerevisiae
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645427
ID:
302645427
8.

Aman_2_1h_R1.fastq.gz

Organism:
Homo sapiens; Saccharomyces cerevisiae
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645426
ID:
302645426
9.

Aman_1_24h_R1.fastq.gz

Organism:
Homo sapiens; Saccharomyces cerevisiae
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645425
ID:
302645425
10.

Aman_1_12h_R1.fastq.gz

Organism:
Homo sapiens; Saccharomyces cerevisiae
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645424
ID:
302645424
11.

Aman_1_8h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645423
ID:
302645423
12.

Aman_1_4h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645422
ID:
302645422
13.

Aman_1_2h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645421
ID:
302645421
14.

Aman_1_1h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645420
ID:
302645420
15.

ActD_2_24h_R1.fastq.gz

Organism:
Homo sapiens; Saccharomyces cerevisiae
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645419
ID:
302645419
16.

ActD_2_12h_R1.fastq.gz

Organism:
Homo sapiens; Saccharomyces cerevisiae
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645418
ID:
302645418
17.

ActD_2_8h_R1.fastq.gz

Organism:
Homo sapiens; Saccharomyces cerevisiae
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645417
ID:
302645417
18.

ActD_2_4h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645416
ID:
302645416
19.

ActD_2_2h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645415
ID:
302645415
20.

ActD_2_1h_R1.fastq.gz

Organism:
Saccharomyces cerevisiae; Homo sapiens
Source name:
HEK293 cells
Platform:
GPL23532
Series:
GSE99517
Download data
Sample
Accession:
GSM2645414
ID:
302645414
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