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Items: 1 to 20 of 969

1.

miR-22 and miR-205 drive tumor aggressiveness of mucoepidermoid carcinomas of salivary glands

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array; Expression profiling by array
Platforms:
GPL15159 GPL17077
70 Samples
Download data: TXT
Series
Accession:
GSE169754
ID:
200169754
2.

miR-22 and miR-205 drive tumor aggressiveness of mucoepidermoid carcinomas of salivary glands [miRNA]

(Submitter supplied) We used miRNA expression arrays and integrated analysis to study mucoepidermoid carcinomas (MEC) to identify potential drivers involved with its pathogenesis. Normal salivary glands were used as controls.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
31 Samples
Download data: TXT
Series
Accession:
GSE169692
ID:
200169692
3.

Dose dependent expression of extracellular microRNAs in HCT116 colorectal cancer cells exposed to high dose rate ionizing radiation

(Submitter supplied) Biomarkers of tumour response to radiotherapy could help in optimising cancer treatment. In this study, we focus on identifying changes in extracellular miRNA as a biomarker of radiation-induced damage to human colorectal cancer cells. HCT116 cells were exposed to increasing doses of X-rays, and extracellular miRNAs were analysed by microarray. The results were correlated with frequencies of micronuclei. more...
Organism:
Homo sapiens; Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
16 Samples
Download data: TXT, XLSX
Series
Accession:
GSE184174
ID:
200184174
4.

Hsa-miR99b/let-7e/miR125a cluster regulates pathogen recognition receptor-stimulated suppressive APCs

(Submitter supplied) Antigen presenting cells (APCs) regulate the balance of our immune response towards microbes. Whereas immunogenic APCs boost inflammation and activate lymphocytes, the highly plastic cells can switch into a tolerogenic/suppressive phenotype that dampens and resolves the response. Thereby the initially mediated inflammation seems to prime the switch of APCs while the strength of activation determines the grade of the suppressive phenotype. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
6 Samples
Download data: TXT
Series
Accession:
GSE114390
ID:
200114390
5.

Blocking and randomization to improve molecular biomarker discovery

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
384 Samples
Download data: TXT
Series
Accession:
GSE109059
ID:
200109059
6.

A unique pair of microarray datasets for microRNA profiling: data without careful design (Dataset B)

(Submitter supplied) We set out to demonstrate the logistic feasibility of careful study design in microarray studies and the level of scientific benefits it can provide, in comparison with post-hoc data adjustment such as normalization, for the purpose of reducing the impact of handling effects on the accuracy and reproducibility of microarray data analysis. Towards this end, we conducted a study of microRNA expression using endometroid endometrial cancer tumors (n=96) and serous ovarian cancer tumors (n=96) that were all primary, untreated, and collected in 2000-2012 at Memorial Sloan Kettering Cancer Center. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
192 Samples
Download data: TXT
Series
Accession:
GSE109058
ID:
200109058
7.

A unique pair of microarray datasets for microRNA profiling: data with careful design (Dataset A)

(Submitter supplied) We set out to demonstrate the logistic feasibility of careful study design in microarray studies and the level of scientific benefits it can provide, in comparison with post-hoc data adjustment such as normalization, for preventing confounding handling effects and improving the accuracy and reproducibility of disease-relevant biomarker detection. Towards this end, we conducted a study of microRNA expression using endometroid endometrial cancer tumors (n=96) and serous ovarian cancer tumors (n=96) that were all primary, untreated, and collected in 2000-2012 at Memorial Sloan Kettering Cancer Center. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
192 Samples
Download data: TXT
Series
Accession:
GSE108838
ID:
200108838
8.

Gene and microRNA modulation upon ET-743 treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL17077 GPL15159
14 Samples
Download data: TXT
Series
Accession:
GSE84939
ID:
200084939
9.

Gene and microRNA modulation upon ET-743 treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line [miRNA expression]

(Submitter supplied) Transcriptional profiling and microRNA profiling of paired PDX and derived cell line MT-CHC01 upon ET-743 treatement Intrahepatic cholangiocarcinoma (ICC) is an aggressive and lethal malignancy with limited therapeutic options. ET-743 has a high antitumor activity in preclinical models of biliary tract carcinoma (BTC), being a promising alternative treatment. Here, we studied the effect of ET-743 at transcriptomic level on an ICC patient derived xenograft (PDX) and on the derived cell line, MT-CHC01. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
8 Samples
Download data: TXT
Series
Accession:
GSE84938
ID:
200084938
10.

Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by array; Non-coding RNA profiling by array
Platforms:
GPL13534 GPL15159
66 Samples
Download data: IDAT, TXT
Series
Accession:
GSE78279
ID:
200078279
11.

Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence [miR-Agilent]

(Submitter supplied) Cervical cancer and a subset of anogenital and head-and-neck carcinomas are caused by persistent infection with high-risk types of the human papillomavirus (hrHPV). Early stages of hrHPV-induced carcinogenesis can be faithfully mimicked in vitro. A major hallmark of hrHPV-transformed cells is their ability to grow anchorage independently, an oncogenic trait known to depend on inactivation of tumour suppressor genes. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
60 Samples
Download data: TXT
Series
Accession:
GSE78278
ID:
200078278
12.

microRNA expression profiles of tumor-positive and tumor-negative sentinel lymph node biopsies from cutaneous melanoma patients

(Submitter supplied) We analyzed microRNA profiles in archival FFPE sentinel node biopsy (SNB) from melanoma patients with different outcomes. Tumor-negative SNB (N), and tumor-positive SNB from patients with (PP) or without disease progression at 5 years follow-up (PN) were analyzed.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
24 Samples
Download data: TXT
Series
Accession:
GSE88727
ID:
200088727
13.

mRNA and miRNA expression profiles for fresh frozen periampullary adenocarcinomas (pancreatobiliary and intestinal type) and adjacent normal tissues.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL15159 GPL14550
182 Samples
Download data: TXT
Series
Accession:
GSE60980
ID:
200060980
14.

mRNA and miRNA expression profiles for fresh frozen periampullary adenocarcinomas (pancreatobiliary and intestinal type) and adjacent normal tissues. [miRNA]

(Submitter supplied) To study the molecular signatures of mRNAs and miRNAs which can potentially act as a prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
89 Samples
Download data: TXT
Series
Accession:
GSE60978
ID:
200060978
15.

Cell-specific microRNA expression patterns in TB patients and household contacts

(Submitter supplied) Monocytes and granulocytes were isolated from blood of TB patients and household contacts. RNA was isolated and microRNA expression was measured using microarrays.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
32 Samples
Download data: TXT
Series
Accession:
GSE70425
ID:
200070425
16.

Epigenetics and Proteomics Join Transcriptomics in the Quest for Tuberculosis Biomarkers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array; Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL13534 GPL15159 GPL20652
102 Samples
Download data: IDAT, TXT
Series
Accession:
GSE70478
ID:
200070478
17.

MicroRNAs and their target genes in gingival tissues.

(Submitter supplied) To gain insights into the in vivo function of miRNAs in the context of periodontitis, we examined the occurrence of miRNAs in healthy and diseased gingival tissues and validated their in silico-predicted targets through mRNA profiling using whole-genome microarrays in the same specimens. Eighty-six individuals with periodontitis contributed 198 gingival papillae: 158 'diseased' (bleeding-on-probing, PD > 4 mm, and AL ≥ 3 mm) and 40 'healthy' (no bleeding, PD ≤ 4 mm, and AL ≤ 2 mm). more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
200 Samples
Download data: TXT
Series
Accession:
GSE54710
ID:
200054710
18.

microRNA expressions in gastric cancer

(Submitter supplied) The study was undertaken to identify microRNAs differently expressed by intestinal type of gastric cancer using miRNA microarray. The miRNA expression in the intestinal type of gastric cancer depending on H. pylori infection suggest that different gastric cancer pathogenesis could be exist between H. pylori-positive and -negative gastric cancer.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
32 Samples
Download data: TXT
Series
Accession:
GSE54397
ID:
200054397
19.

miRNA expression profiles in the 19 candidate urines (prostate cancer, CaP, patients and non-cancer subjects with benign prostatic hyperplasia, BPH)

(Submitter supplied) The aims of the study were investigated whether expression of urinary cell-free miRNAs would be different between prostate cancer (CaP) patients and non-cancer subjects with benign prostatic hyperplasia (BPH). Urinary cell-free miRNAs will provide potential benefits for detecting CaP, and virus-encoded hsv1-miR-H18 and hsv2-miR-H9-5p could be the important urinary diagnostic markers of CaP. It would be interesting because this is the first report about virus-encoded miRNAs related to CaP, and two miRNAs showed good diagnostic performance even in patients with PSA gray zone.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15159
19 Samples
Download data: TXT
Series
Accession:
GSE54010
ID:
200054010
20.

Characterization of mRNA and microRNA expression profiles in solid-pseudopapillary neoplasm of pancreas, ductal adenocarcinoma and pancreatic neuroendocrine tumors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL15159 GPL10558
62 Samples
Download data: TXT
Series
Accession:
GSE43797
ID:
200043797
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