“prostate cancer”[Title] AND "Homo sapiens"[porgn:__txid9606] AND gds[ - GEO DataSets

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Select item 61001.

MicroRNA-135b overexpression effect on prostate cancer cell line: time course

Analysis of LNCaP prostate cancer (PCa) cells overexpressing miRNA-135b for up to 36 hours. LNCaP cells express the androgen receptor (AR). MiRNA-135b overexpression in AR+ PCa cells results in slower growth compared to AR knockdown. Results provide insight into the basis of this slower growth.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol, 3 time sets

Platform:: GPL10558
Series:: GSE57820
12 Samples

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DataSet

Accession:: GDS6100

ID:: 6100

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 58052.

Peptidyl-prolyl cis/trans isomerase Pin1 deficiency effect on prostate cancer cells

Analysis of prostate cancer (PC) cell lines LNCap (androgen-dependent) and DU145 (androgen-independent) following siRNA-mediated knockdown of Peptidyl-prolyl cis/trans isomerase Pin1. Results provide insight into molecular mechanisms underlying Pin1 modulation of both PC two cell lines.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 cell line, 3 protocol sets

Platform:: GPL6244
Series:: GSE67457
6 Samples

Download data: CEL

DataSet

Accession:: GDS5805

ID:: 5805

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 58043.

PI3K/mTOR Inhibitor NVP-BEZ235 and taxotere effects on prostate cancer xenograft tumors

Analysis of DU145 xenograft tumors in NOD/SCID mice treated with NVP-BEZ235, taxotere, or both. NVP-BEZ235 targets prostate cancer progenitor cells. Taxotere targets the bulk tumor. Results provide insight into potential biomarkers associated with cancer stem cells in these xenograft tumors.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 agent sets

Platform:: GPL570
Series:: GSE49232
4 Samples

Download data: CEL

DataSet

Accession:: GDS5804

ID:: 5804

Select item 54404.

Androgen effect on carboxyl terminal-binding protein 2-deficient prostate cancer cell line

Analysis of androgen receptor (AR)-positive LNCaP prostate cancer cells depleted for carboxyl terminal-binding protein 2 (CTBP2) then treated with the androgen, dihydrotestosterone (DHT). Results provide insight into the molecular effects of CtBP2 knockdown on AR-mediated gene regulation.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 4 genotype/variation sets

Platform:: GPL6244
Series:: GSE58309
10 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5440

ID:: 5440

Select item 56065.

Androgen effect on runt-related transcription factor 1-deficient prostate cancer cell line

Analysis of androgen receptor (AR)-positive prostate cancer (PC) LNCaP cells depleted for runt-related transcription factor (RUNX1) by siRUNX1 transfection then treated with 10nM dihydrotestosterone (DHT). Results provide insight into the role of RUNX1 in AR-dependent PC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE62454
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5606

ID:: 5606

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 49516.

Lysophosphatidic acid effect on breast and prostate cancer cell lines

Analysis of MDA-MB-231, MCF7 and PC3 cells treated with lysophosphatidic acid (LPA). LPA activates six different G protein-coupled receptors (LPA receptors 1-6). Results provide insight into LPA-induced genes among three unrelated cancer cell lines expressing different patterns of LPA receptors.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 3 cell line sets

Platform:: GPL570
Series:: GSE56265
12 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4951

ID:: 4951

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 49527.

BET bromodomain inhibitor I-BET762 effect on prostate cancer cell lines: dose response

Analysis of prostate cancer (PC) cell lines (NCI-H660, VCaP, LNCaP, PC-3) treated with I-BET762 at 0.5uM or 10uM for 24hr. I-BET762 is a highly specific inhibitor of BET (bromodomain and extra-terminal) proteins. Results provide insight into molecular pathways regulated by I-BET762 treatment in PC.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 cell line, 3 dose sets

Platform:: GPL570
Series:: GSE56352
24 Samples

Download data: CEL

DataSet

Accession:: GDS4952

ID:: 4952

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 53738.

miR-221 expression effect on prostate cancer cell line

Analysis of PC-3 prostate cancer cells expressing pre-miR-221. miR-221 is frequently downregulated in primary prostate cancer. Results provide insight into the role of miR-221 in the pathogenesis of prostate cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL570
Series:: GSE45627
4 Samples

Download data: CEL

DataSet

Accession:: GDS5373

ID:: 5373

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 48249.

Prostate cancer

Analysis of malignant and benign prostate tissues. Results provide insight into a gene expression signature for prostate cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 3 genotype/variation sets

Platform:: GPL570
Series:: GSE55945
21 Samples

Download data: CEL

DataSet

Accession:: GDS4824

ID:: 4824

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 522210.

U2OS osteosarcoma cell line response to strigolactone analogs ST362 and MEB55: 24 hours

Analysis of U2OS cells treated with strigolactone (SL) analog ST362 or MEB55 for 24hr. SL is a plant hormone. SL analogs potently inhibit growth of breast cancer cells. Results provide insight into molecular mechanisms underlying the anti-tumorigenic effects of SL analogs towards cancer cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL10558
Series:: GSE54820
6 Samples

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DataSet

Accession:: GDS5222

ID:: 5222

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 522111.

U2OS osteosarcoma cell line response to strigolactone analogs ST362 and MEB55: 6 hours

Analysis of U2OS cells treated with strigolactone (SL) analog ST362 or MEB55 for 6hr. SL is a plant hormone. SL analogs potently inhibit growth of breast cancer cells. Results provide insight into molecular mechanisms underlying the anti-tumorigenic effects of SL analogs towards cancer cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL10558
Series:: GSE54820
6 Samples

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DataSet

Accession:: GDS5221

ID:: 5221

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 495712.

FOXA1 overexpression effect on prostate cancer cell line

Analysis of LNCaP prostate cancer cells overexpressing FOXA1. FOXA1 is a key member of the androgen receptor (AR) transcription factor complex. Results provide insight into the role of FOXA1 in prostate cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol sets

Platform:: GPL10558
Series:: GSE49153
12 Samples

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DataSet

Accession:: GDS4957

ID:: 4957

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 482913.

VprBP depletion effect on prostate cancer cell line

Analysis of DU145 prostate cancer cells depleted for Vpr binding protein (VPRBP). VPRBP knockdown decreases histone H2A threonine 120 (H2AT120) phosphorylation and impairs the viability of DU145 cells. Results provide insight into the role of VprBP in regulating gene transcription.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL10558
Series:: GSE50414
4 Samples

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DataSet

Accession:: GDS4829

ID:: 4829

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 496414.

Telomere-elongated, prostate cancer cells

Analysis of telomere-elongated PC-3 prostate cancer cells in the presence of exogenous human telomerase reverse transcriptase (hTERT). Forced elongation of telomeres promotes PC-3 cell differentiation. Results provide insight into the influence of telomere length on tumor malignancy.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets

Platform:: GPL570
Series:: GSE41559
16 Samples

Download data: CEL

DataSet

Accession:: GDS4964

ID:: 4964

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 507215.

High grade prostate cancer

Analysis of prostate cancer cells microdissected from high grade prostate cancer tumor samples. Results identify a gene expression signature for high grade prostate cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 3 other sets

Platform:: GPL570
Series:: GSE45016
11 Samples

Download data: CEL

DataSet

Accession:: GDS5072

ID:: 5072

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 517316.

G-protein coupled receptor kinase 3 expression effect on prostate cancer cell line

Analysis of PC3 prostate cancer cells expressing G-protein coupled receptor kinase 3 (GRK3). Results provide insight into the role of GRK3 in prostate cancer progression and metastasis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL6883
Series:: GSE36022
6 Samples

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DataSet

Accession:: GDS5173

ID:: 5173

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 439517.

External beam radiation therapy effect on prostate cancer patients: peripheral white blood cells

Analysis of peripheral blood from men with non-metastatic prostate cancer (PC) on days 1, 7, 14, 21, 42 of external beam radiation therapy (EBRT), and at 30 days post-EBRT. Fatigue is a common side effect of EBRT. Results provide insight into molecular basis of fatigue in men with PC during EBRT.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 20 individual, 2 protocol, 8 time sets

Platform:: GPL570
Series:: GSE30174
80 Samples

Download data: CEL

DataSet

Accession:: GDS4395

ID:: 4395

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 484618.

MED1 overexpression effect on prostate cancer cell line

Analysis of LNCaP prostate cancer cells overexpressing the Mediator of RNA polymerase II transcription factor 1 (MED1). MED1 is a coactivator of the androgen receptor and other signal-activated transcription factors. Results provide insight into the role of MED1 overexpression in prostate cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL571
Series:: GSE41150
4 Samples

Download data: CEL

DataSet

Accession:: GDS4846

ID:: 4846

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 412419.

Genetic reprogramming of prostate cancer-associated stromal cells

Analysis of induced pluripotent stem cells (iPSCs) obtained from sorted CD90+ prostate cancer (CP)-associated stromal cells cultured and transfected with stem cell transcription factor POU5F1/LIN28/NANOG/SOX2 expression vectors. Results provide insight into the stemness of CP stromal-derived iPSCs.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 cell type, 2 protocol sets

Platform:: GPL570
Series:: GSE35373
6 Samples

Download data: CEL

DataSet

Accession:: GDS4124

ID:: 4124

Select item 412320.

Isoflavone and 3,3’-diindolylmethane effect on C4-2B prostate cancer cells

Analysis of C4-2B prostate cancer (PCa) cells treated with isoflavone (IsoF) and 3,3’- diindolylmethane (B-DIM) for up to 72 hours. IsoF and B-DIM inhibited the signal transductions in PCa signaling. Results provide insight into molecular mechanisms underlying PCa growth.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent, 4 time sets

Platform:: GPL570
Series:: GSE35324
5 Samples

Download data: CEL

DataSet

Accession:: GDS4123

ID:: 4123

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

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