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Full record GDS2327

Transgenic T-cell receptor model of tolerant CD8+ T cells

Analysis of tolerant, naïve, and memory CD8+ T cells purified from TCRxGag transgenics. T cell tolerance to self-proteins prevents autoimmunity but impedes the response to tumor-associated antigens. Results provide insight into the feasibility of rescuing tolerant cells for tumor immunotherapy.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL1073
Series:
GSE3800
6 Samples
Download data: CEL
DataSet
Accession:
GDS2327
ID:
2327

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