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Search results: x Variables, w Analyses, x Documents, and z Datasets in x Studies
Clinical VariableDatasetVariable DescriptionVariable ID
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) III Question 21B - Rapid alternating movements of hands (pronation-supination movements of hands, vertically or horizontally, with as large an amplitude as possible, both hands simultaneously), left hand: 0 = Normal; 0.5=Intermediate between normal and mild slowing and/or reduction in amplitude; 1 = Mild slowing and/or reduction in amplitude; 1.5=Intermediate between mild slowing and/or reduction in amplitude and moderately impaired, definite and early fatiguing, may have occasional arrests in movement; 2 = Moderately impaired, definite and early fatiguing, may have occasional arrests in movement; 2.5=Intermediate between moderately impaired, definite and early fatiguing, may have occasional arrests in movement and severely impaired, frequent hesitation in initiating movements or arrests in ongoing movement ; 3 = Severely impaired, frequent hesitation in initiating movements or arrests in ongoing movement; 3.5=Intermediate between severely impaired, frequent hesitation in initiating movements or arrests in ongoing movement and can barely perform the task; 4 = Can barely perform the task; U = Unavailablephv00045228.v1.p1
Family ID, subject ID, mother ID, father ID, and gender of participants with or without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
Unique subject IDphv00051860.v2.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) II Question 10 - Freezing when walking: 0 = None; 1 = Rare freezing when walking, may have start hesitation; 2 = Occasional freezing when walking; 3 = Frequent freezing, occasionally falls from freezing; 4 = Frequent falls because of freezing; U = Unavailablephv00045205.v1.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) III Question 20A - Hand movements (subject opens and closes hands in rapid succession with widest amplitude possible, each hand separately). Right hand: 0 = Normal; 0.5=Intermediate between normal and mild slowing and/or reduction in amplitude; 1 = Mild slowing and/or reduction in amplitude; 1.5=Intermediate between mild slowing and/or reduction in amplitude and moderately impaired, definite and early fatiguing, may have occasional arrests in movement ; 2 = Moderately impaired, definite and early fatiguing, may have occasional arrests in movement; 2.5=Intermediate between moderately impaired, definite and early fatiguing, may have occasional arrests in movement and severely impaired, frequent hesitation in initiating movements or arrests in ongoing movement; 3 = Severely impaired, frequent hesitation in initiating movements or arrests in ongoing movement; 3.5=Intermediate between severely impaired, frequent hesitation in initiating movements or arrests in ongoing movement and can barely perform the task; 4 = Can barely perform the task; U = Unavailablephv00045225.v1.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) II Question 7 - Hygiene: 0 = Normal; 1 = Somewhat slow, but no help needed; 2 = Needs help to shower or bathe, very slow in hygienic care; 3 = Requires assistance for washing, brushing teeth, combing hair, going to bathroom; 4 = Needs Foley catheter or other mechanical aids; U = Unavailablephv00045202.v1.p1
Family ID, subject ID, mother ID, father ID, and gender of participants with or without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
Sexphv00051863.v2.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) II Question 4 - Handwriting: 0 = Normal; 1 = Slightly slow or small; 2 = Moderately slow or small, all words are legible; 3 = Severely affected, not all words are legible; 4 = The majority of words are not legible; U = Unavailablephv00045199.v1.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) II Question 1 - Speech: 0 = Normal; 1 = Mildly affected, no difficulty being understood; 2 = Moderately affected, sometimes asked to repeat statements; 3 = Severely affected, frequently asked to repeat statements; 4 = Unintelligible most of the time; U = Unavailablephv00045196.v1.p1
Subject ID, family number, type of control, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age at enrollment, gender, race, ethnicity, subject's country of birth, family history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, of brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of migraine, of muscle disease, of obsessive compulsive disorder, of other known medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of suicide attempt, of Tourette's syndrome, participant history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of multiple scleroses, muscle disease, obsessive compulsive disorder, of other medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of a past suicide attempt, of Tourette's syndrome, Mini Mental Status Score, subject hand preference, subject either did (yes) or did not (no) undergo a neurological examination, and smoking status of participants without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
The presence or absence of depression in the subjects themselves as documented based on clinician interview (see phs000004: NINDS Repository Neurologically Normal Control Collection)phv00045279.v1.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
Ethnicityphv00045173.v1.p1
Subject ID, family number, type of control, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age at enrollment, gender, race, ethnicity, subject's country of birth, family history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, of brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of migraine, of muscle disease, of obsessive compulsive disorder, of other known medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of suicide attempt, of Tourette's syndrome, participant history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of multiple scleroses, muscle disease, obsessive compulsive disorder, of other medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of a past suicide attempt, of Tourette's syndrome, Mini Mental Status Score, subject hand preference, subject either did (yes) or did not (no) undergo a neurological examination, and smoking status of participants without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
The presence or absence of brain aneurysm in the subjects themselves as documented based on clinician interview (see phs000004: NINDS Repository Neurologically Normal Control Collection)phv00045276.v1.p1
Subject ID, family number, type of control, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age at enrollment, gender, race, ethnicity, subject's country of birth, family history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, of brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of migraine, of muscle disease, of obsessive compulsive disorder, of other known medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of suicide attempt, of Tourette's syndrome, participant history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of multiple scleroses, muscle disease, obsessive compulsive disorder, of other medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of a past suicide attempt, of Tourette's syndrome, Mini Mental Status Score, subject hand preference, subject either did (yes) or did not (no) undergo a neurological examination, and smoking status of participants without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
The presence or absence of epilepsy in the subject blood relatives, to be delineated, as documented based on clinician interview of the subject (see phs000004: NINDS Repository Neurologically Normal Control Collection)phv00045257.v1.p1
Subject ID, subject source, source subject ID, consent group, and affection status of participants with or without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
Consent group as determined by DACphv00054646.v2.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
Presence of postural instabilityphv00045180.v1.p1
Subject ID, family number, type of control, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age at enrollment, gender, race, ethnicity, subject's country of birth, family history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, of brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of migraine, of muscle disease, of obsessive compulsive disorder, of other known medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of suicide attempt, of Tourette's syndrome, participant history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of multiple scleroses, muscle disease, obsessive compulsive disorder, of other medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of a past suicide attempt, of Tourette's syndrome, Mini Mental Status Score, subject hand preference, subject either did (yes) or did not (no) undergo a neurological examination, and smoking status of participants without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
The presence or absence of muscle disease of any type in the subject blood relatives, to be delineated, as documented based on clinician interview of the subject (see phs000004: NINDS Repository Neurologically Normal Control Collection)phv00045263.v1.p1
Subject ID, subject source, source subject ID, consent group, and affection status of participants with or without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
Affection statusphv00054649.v2.p1
Subject ID, family number, type of control, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age at enrollment, gender, race, ethnicity, subject's country of birth, family history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, of brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of migraine, of muscle disease, of obsessive compulsive disorder, of other known medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of suicide attempt, of Tourette's syndrome, participant history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of multiple scleroses, muscle disease, obsessive compulsive disorder, of other medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of a past suicide attempt, of Tourette's syndrome, Mini Mental Status Score, subject hand preference, subject either did (yes) or did not (no) undergo a neurological examination, and smoking status of participants without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
The presence or absence of memory loss in the subject blood relatives, to be delineated, as documented based on clinician interview of the subject (see phs000004: NINDS Repository Neurologically Normal Control Collection)phv00045260.v1.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) III Question 26 - Postural Stability (response to sudden posterior displacement produced by pull on shoulders while subject is erect, with eyes open and feet slightly apart; subject is prepared): 0 = Normal; 0.5=Intermediate between normal and retropulsion, but recovers unaided; 1 = Retropulsion, but recovers unaided; 1.5=Intermediate between retropulsion, but recovers unaided and absence of postural response, would fall if not caught by examiner; 2 = Absence of postural response, would fall if not caught by examiner; 2.5=Intermediate between absence of postural response, would fall if not caught by examiner and very unstable, tends to lose balance spontaneously; 3 = Very unstable, tends to lose balance spontaneously; 3.5=Intermediate between very unstable, tends to lose balance spontaneously and unable to stand without assistance; 4 = Unable to stand without assistance; U = Unavailablephv00045234.v1.p1
Subject ID, family number, type of control, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age at enrollment, gender, race, ethnicity, subject's country of birth, family history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, of brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of migraine, of muscle disease, of obsessive compulsive disorder, of other known medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of suicide attempt, of Tourette's syndrome, participant history of amyotrophic lateral sclerosis, of ataxia, of autism, of bipolar disorder, brain aneurysm, of cancer, of dementia, of depression, of diabetes, of dystonia, of epilepsy, of heart disease, of hypertension, of memory loss, of migraine, of multiple scleroses, muscle disease, obsessive compulsive disorder, of other medical illnesses, of Parkinson disease, of schizophrenia, of cerebrovascular disease, of a past suicide attempt, of Tourette's syndrome, Mini Mental Status Score, subject hand preference, subject either did (yes) or did not (no) undergo a neurological examination, and smoking status of participants without Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
Poor data quality for copy number variant data (standard deviation for log R ratio for chromosome 1 above 0.25)phv00065483.v1.p1
Subject ID, affection status, family number, individual is known to harbor a LRRK2 mutation, source of DNA, clean dataset used to create marker QC filter thresholds, clean dataset used to perform \"pre-computes\" of association analyses, the main cluster derived from the first two components of the multidimensional scaling algorithm, call rate below 96%, poor data quality for copy number variant data, XO (only one X chromosome and no Y chromosome observed) or XO mosaic - possible Turner syndrome, probable artifact of the cell line, age of onset of Parkinson disease symptoms, year of birth, year of study visit, gender, race, ethnicity, family history of Parkinson disease, participant history of traumatic brain injury, of strokes, of encephalitis, oculogyric crisis, of suggesting Alzheimer disease or other dementing illness, asymmetric onset of disease symptoms, bradykinesia, resting tremor, rigidity, postural instability, gait dysfunction, sustained remission of parkinsonian symptoms, supranuclear gaze palsy with downgaze less than 50% of normal, cerebellar signs, Hoehn and Yahr stage, Unified Parkinson's Disease Rating Scale II, Unified Parkinson's Disease Rating Scale III, Mini-Mental Status Exam total score, smoking status, and marked response to levodopa therapy of participants with Parkinson disease and involved in the \"CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)\" project.
UPRDS (Unified Parkinson Disease Rating Scale) III Question 23 - Arising from chair (subject attempts to arise from a straight-back wood or metal chair, with arms folded across chest): 0 = Normal; 0.5=Intermediate between normal and slow or may need more than one attempt; 1 = Slow or may need more than one attempt; 1.5=Intermediate between slow or may need more than one attempt and pushes self up from arms of seat; 2 = Pushes self up from arms of seat; 2.5=Intermediate between pushes self up from arms of seat and tends to fall back and may have to try more than one time but can get up without help; 3 = Tends to fall back and may have to try more than one time but can get up without help; 3.5=Intermediate between tends to fall back and may have to try more than one time but can get up without help and unable to arise without help; 4 = Unable to arise without help; U = Unavailablephv00045231.v1.p1
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