| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | Subject's country of birth | phv00020523.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The clinician indicates if 'acute' or 'chronic' denervation, or 'acute' and 'chronic' denervation, or 'no denervation' is present in the bulbar regions of the body. If the region was not examined, the clinician indicates 'not tested'. | phv00000374.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The clinician indicates the site of onset of the progressive weakness (i.e. bulbar, truncal, generalized, respiratory, limb). | phv00000417.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The clinician indicates if 'acute' or 'chronic' denervation, or 'acute' and 'chronic' denervation, or 'no denervation' is present in the thoracic region of the body. If the region was not examined, the clinician indicates 'not tested'. | phv00000377.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | Gender of the subject | phv00020520.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | 'Present' means that the individual subject indicates during clinician's interview that there is a medical history of dystonia. 'Absent' means that the subject does not have a medical history of the disorder. | phv00000394.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The clinician indicates if and where there are 'definite', 'indeterminate', or 'absent' upper motor neuron signs in the cervical region. If the region was not examined, the clinician indicates 'not tested'. | phv00000414.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | 'Present' means that the individual subject indicates during clinician's interview that there is a medical history of hypertension. 'Absent' means that the subject does not have a medical history of the disorder. | phv00000397.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | Race of the subject | phv00000371.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | 'Present' means that the individual subject indicates during clinician's interview that there is a medical history of dementia. 'Absent' means that the subject does not have a medical history of the disorder. | phv00000391.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The clinician indicates whether the patient has fronto-temporal dementia (or any other neurological impairment, or NA). | phv00000408.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The clinician indicates if and where there are 'definite', 'indeterminate', or 'absent' lower motor neuron signs in the lumbo-sacral region. If the region was not examined, the clinician indicates 'not tested'. | phv00000411.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | 'Present' means that the individual subject indicates during clinician's interview that there is a medical history of Alzheimer's disease. 'Absent' means that the subject does not have a medical history of the disease. | phv00000385.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | Age, at sampling, of the subject | phv00000368.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | 'Present' means that the individual subject indicates during clinician's interview that there is a medical history of bipolar disorder. 'Absent' means that the subject does not have a medical history of the disorder. | phv00000388.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The hand preference of the subject; the subject's dominant hand. | phv00000405.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | 'Present' means that the individual subject indicates during clinician's interview that there is a medical history of brain aneurysm. 'Absent' means that the subject does not have a medical history of the disorder. | phv00000389.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | Ethnic category (as reported by subject) - check one: Hispanic or Latino, Not Hispanic or Latino | phv00000372.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | 'Present' means that the individual subject indicates during clinician's interview that there is a medical history of depression. 'Absent' means that the subject does not have a medical history of the disorder. | phv00000392.v1.p1 |
| This table contains ALS phenotype data (n=1790) of the NINDS DNA and Cell Line Repository, which was obtained using the NINDS Repository Clinical Data Elements questionnaire for ALS (phd000106). Disease information collected with this questionnaire provides a standardized set of data that can be used to identify study inclusion and exclusion criteria, the presence of sporadic ALS symptoms described in the El Escorial Criteria, family and medical histories, and socio-demographic information. Study inclusion criteria were queried through questions about, e.g. location of onset of symptoms, type of motor neurons involved (upper, lower, bulbar), current treatment and information about genetic tests taken; study exclusion criteria were queried by identifying information (e.g. electrophysiological or imaging test results, medical or family histories etc.) that might suggest the presence of a different and potentially confounding diagnosis. | The clinician indicates if and where there are 'definite', 'indeterminate', or 'absent' lower motor neuron signs in the bulbar region. If the region was not examined, the clinician indicates 'not tested'. | phv00000409.v1.p1 |