ClinVar Genomic variation as it relates to human health
NM_002880.4(RAF1):c.1917G>A (p.Leu639=)
Germline
Classification
(3)
Likely benign
criteria provided, multiple submitters, no conflicts
Somatic
No data submitted for somatic clinical impact
Somatic
No data submitted for oncogenicity
Genes
Gene | OMIM | ClinGen Gene Dosage Sensitivity Curation | Variation Viewer | Related variants | ||
---|---|---|---|---|---|---|
HI score | TS score | Within gene | All | |||
RAF1 | No evidence available | No evidence available |
GRCh38 GRCh37 |
1060 | 1117 |
Conditions - Germline
Condition | Classification
(# of submissions) |
Review status | Last evaluated | Variation/condition record |
---|---|---|---|---|
Likely benign (1) |
|
Jul 9, 2020 | RCV002410634.1 | |
Likely benign (1) |
|
Oct 11, 2023 | RCV003097348.2 | |
Likely benign (1) |
|
Dec 9, 2020 | RCV003896182.1 |
Citations for germline classification of this variant
HelpText-mined citations for this variant ...
HelpRecord last updated Mar 17, 2024