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NM_007294.4(BRCA1):c.4096+15T>C AND not specified

Germline classification:
Likely benign (1 submission)
Last evaluated:
Feb 24, 2020
Review status:
1 star out of maximum of 4 stars
criteria provided, single submitter
Somatic classification
of clinical impact:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of oncogenicity:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Record status:
current
Accession:
RCV001174825.2

Allele description [Variation Report for NM_007294.4(BRCA1):c.4096+15T>C]

NM_007294.4(BRCA1):c.4096+15T>C

Genes:
BRCA1:BRCA1 DNA repair associated [Gene - OMIM - HGNC]
LOC126862571:BRD4-independent group 4 enhancer GRCh37_chr17:41243136-41244335 [Gene]
Variant type:
single nucleotide variant
Cytogenetic location:
17q21.31
Genomic location:
Preferred name:
NM_007294.4(BRCA1):c.4096+15T>C
HGVS:
  • NC_000017.11:g.43091420A>G
  • NG_005905.2:g.126564T>C
  • NG_087068.1:g.402A>G
  • NM_001407571.1:c.3883+15T>C
  • NM_001407581.1:c.4096+15T>C
  • NM_001407582.1:c.4096+15T>C
  • NM_001407583.1:c.4096+15T>C
  • NM_001407585.1:c.4096+15T>C
  • NM_001407587.1:c.4093+15T>C
  • NM_001407590.1:c.4093+15T>C
  • NM_001407591.1:c.4093+15T>C
  • NM_001407593.1:c.4096+15T>C
  • NM_001407594.1:c.4096+15T>C
  • NM_001407596.1:c.4096+15T>C
  • NM_001407597.1:c.4096+15T>C
  • NM_001407598.1:c.4096+15T>C
  • NM_001407602.1:c.4096+15T>C
  • NM_001407603.1:c.4096+15T>C
  • NM_001407605.1:c.4096+15T>C
  • NM_001407610.1:c.4093+15T>C
  • NM_001407611.1:c.4093+15T>C
  • NM_001407612.1:c.4093+15T>C
  • NM_001407613.1:c.4093+15T>C
  • NM_001407614.1:c.4093+15T>C
  • NM_001407615.1:c.4093+15T>C
  • NM_001407616.1:c.4096+15T>C
  • NM_001407617.1:c.4096+15T>C
  • NM_001407618.1:c.4096+15T>C
  • NM_001407619.1:c.4096+15T>C
  • NM_001407620.1:c.4096+15T>C
  • NM_001407621.1:c.4096+15T>C
  • NM_001407622.1:c.4096+15T>C
  • NM_001407623.1:c.4096+15T>C
  • NM_001407624.1:c.4096+15T>C
  • NM_001407625.1:c.4096+15T>C
  • NM_001407626.1:c.4096+15T>C
  • NM_001407627.1:c.4093+15T>C
  • NM_001407628.1:c.4093+15T>C
  • NM_001407629.1:c.4093+15T>C
  • NM_001407630.1:c.4093+15T>C
  • NM_001407631.1:c.4093+15T>C
  • NM_001407632.1:c.4093+15T>C
  • NM_001407633.1:c.4093+15T>C
  • NM_001407634.1:c.4093+15T>C
  • NM_001407635.1:c.4093+15T>C
  • NM_001407636.1:c.4093+15T>C
  • NM_001407637.1:c.4093+15T>C
  • NM_001407638.1:c.4093+15T>C
  • NM_001407639.1:c.4096+15T>C
  • NM_001407640.1:c.4096+15T>C
  • NM_001407641.1:c.4096+15T>C
  • NM_001407642.1:c.4096+15T>C
  • NM_001407644.1:c.4093+15T>C
  • NM_001407645.1:c.4093+15T>C
  • NM_001407646.1:c.4087+15T>C
  • NM_001407647.1:c.4087+15T>C
  • NM_001407648.1:c.3973+15T>C
  • NM_001407649.1:c.3970+15T>C
  • NM_001407652.1:c.4096+15T>C
  • NM_001407653.1:c.4018+15T>C
  • NM_001407654.1:c.4018+15T>C
  • NM_001407655.1:c.4018+15T>C
  • NM_001407656.1:c.4018+15T>C
  • NM_001407657.1:c.4018+15T>C
  • NM_001407658.1:c.4018+15T>C
  • NM_001407659.1:c.4015+15T>C
  • NM_001407660.1:c.4015+15T>C
  • NM_001407661.1:c.4015+15T>C
  • NM_001407662.1:c.4015+15T>C
  • NM_001407663.1:c.4018+15T>C
  • NM_001407664.1:c.3973+15T>C
  • NM_001407665.1:c.3973+15T>C
  • NM_001407666.1:c.3973+15T>C
  • NM_001407667.1:c.3973+15T>C
  • NM_001407668.1:c.3973+15T>C
  • NM_001407669.1:c.3973+15T>C
  • NM_001407670.1:c.3970+15T>C
  • NM_001407671.1:c.3970+15T>C
  • NM_001407672.1:c.3970+15T>C
  • NM_001407673.1:c.3970+15T>C
  • NM_001407674.1:c.3973+15T>C
  • NM_001407675.1:c.3973+15T>C
  • NM_001407676.1:c.3973+15T>C
  • NM_001407677.1:c.3973+15T>C
  • NM_001407678.1:c.3973+15T>C
  • NM_001407679.1:c.3973+15T>C
  • NM_001407680.1:c.3973+15T>C
  • NM_001407681.1:c.3973+15T>C
  • NM_001407682.1:c.3973+15T>C
  • NM_001407683.1:c.3973+15T>C
  • NM_001407684.1:c.4096+15T>C
  • NM_001407685.1:c.3970+15T>C
  • NM_001407686.1:c.3970+15T>C
  • NM_001407687.1:c.3970+15T>C
  • NM_001407688.1:c.3970+15T>C
  • NM_001407689.1:c.3970+15T>C
  • NM_001407690.1:c.3970+15T>C
  • NM_001407691.1:c.3970+15T>C
  • NM_001407692.1:c.3955+15T>C
  • NM_001407694.1:c.3955+15T>C
  • NM_001407695.1:c.3955+15T>C
  • NM_001407696.1:c.3955+15T>C
  • NM_001407697.1:c.3955+15T>C
  • NM_001407698.1:c.3955+15T>C
  • NM_001407724.1:c.3955+15T>C
  • NM_001407725.1:c.3955+15T>C
  • NM_001407726.1:c.3955+15T>C
  • NM_001407727.1:c.3955+15T>C
  • NM_001407728.1:c.3955+15T>C
  • NM_001407729.1:c.3955+15T>C
  • NM_001407730.1:c.3955+15T>C
  • NM_001407731.1:c.3955+15T>C
  • NM_001407732.1:c.3955+15T>C
  • NM_001407733.1:c.3955+15T>C
  • NM_001407734.1:c.3955+15T>C
  • NM_001407735.1:c.3955+15T>C
  • NM_001407736.1:c.3955+15T>C
  • NM_001407737.1:c.3955+15T>C
  • NM_001407738.1:c.3955+15T>C
  • NM_001407739.1:c.3955+15T>C
  • NM_001407740.1:c.3952+15T>C
  • NM_001407741.1:c.3952+15T>C
  • NM_001407742.1:c.3952+15T>C
  • NM_001407743.1:c.3952+15T>C
  • NM_001407744.1:c.3952+15T>C
  • NM_001407745.1:c.3952+15T>C
  • NM_001407746.1:c.3952+15T>C
  • NM_001407747.1:c.3952+15T>C
  • NM_001407748.1:c.3952+15T>C
  • NM_001407749.1:c.3952+15T>C
  • NM_001407750.1:c.3955+15T>C
  • NM_001407751.1:c.3955+15T>C
  • NM_001407752.1:c.3955+15T>C
  • NM_001407838.1:c.3952+15T>C
  • NM_001407839.1:c.3952+15T>C
  • NM_001407841.1:c.3952+15T>C
  • NM_001407842.1:c.3952+15T>C
  • NM_001407843.1:c.3952+15T>C
  • NM_001407844.1:c.3952+15T>C
  • NM_001407845.1:c.3952+15T>C
  • NM_001407846.1:c.3952+15T>C
  • NM_001407847.1:c.3952+15T>C
  • NM_001407848.1:c.3952+15T>C
  • NM_001407849.1:c.3952+15T>C
  • NM_001407850.1:c.3955+15T>C
  • NM_001407851.1:c.3955+15T>C
  • NM_001407852.1:c.3955+15T>C
  • NM_001407853.1:c.3883+15T>C
  • NM_001407854.1:c.4096+15T>C
  • NM_001407858.1:c.4096+15T>C
  • NM_001407859.1:c.4096+15T>C
  • NM_001407860.1:c.4093+15T>C
  • NM_001407861.1:c.4093+15T>C
  • NM_001407862.1:c.3895+15T>C
  • NM_001407863.1:c.3973+15T>C
  • NM_001407874.1:c.3892+15T>C
  • NM_001407875.1:c.3892+15T>C
  • NM_001407879.1:c.3886+15T>C
  • NM_001407881.1:c.3886+15T>C
  • NM_001407882.1:c.3886+15T>C
  • NM_001407884.1:c.3886+15T>C
  • NM_001407885.1:c.3886+15T>C
  • NM_001407886.1:c.3886+15T>C
  • NM_001407887.1:c.3886+15T>C
  • NM_001407889.1:c.3886+15T>C
  • NM_001407894.1:c.3883+15T>C
  • NM_001407895.1:c.3883+15T>C
  • NM_001407896.1:c.3883+15T>C
  • NM_001407897.1:c.3883+15T>C
  • NM_001407898.1:c.3883+15T>C
  • NM_001407899.1:c.3883+15T>C
  • NM_001407900.1:c.3886+15T>C
  • NM_001407902.1:c.3886+15T>C
  • NM_001407904.1:c.3886+15T>C
  • NM_001407906.1:c.3886+15T>C
  • NM_001407907.1:c.3886+15T>C
  • NM_001407908.1:c.3886+15T>C
  • NM_001407909.1:c.3886+15T>C
  • NM_001407910.1:c.3886+15T>C
  • NM_001407915.1:c.3883+15T>C
  • NM_001407916.1:c.3883+15T>C
  • NM_001407917.1:c.3883+15T>C
  • NM_001407918.1:c.3883+15T>C
  • NM_001407919.1:c.3973+15T>C
  • NM_001407920.1:c.3832+15T>C
  • NM_001407921.1:c.3832+15T>C
  • NM_001407922.1:c.3832+15T>C
  • NM_001407923.1:c.3832+15T>C
  • NM_001407924.1:c.3832+15T>C
  • NM_001407925.1:c.3832+15T>C
  • NM_001407926.1:c.3832+15T>C
  • NM_001407927.1:c.3832+15T>C
  • NM_001407928.1:c.3832+15T>C
  • NM_001407929.1:c.3832+15T>C
  • NM_001407930.1:c.3829+15T>C
  • NM_001407931.1:c.3829+15T>C
  • NM_001407932.1:c.3829+15T>C
  • NM_001407933.1:c.3832+15T>C
  • NM_001407934.1:c.3829+15T>C
  • NM_001407935.1:c.3832+15T>C
  • NM_001407936.1:c.3829+15T>C
  • NM_001407937.1:c.3973+15T>C
  • NM_001407938.1:c.3973+15T>C
  • NM_001407939.1:c.3973+15T>C
  • NM_001407940.1:c.3970+15T>C
  • NM_001407941.1:c.3970+15T>C
  • NM_001407942.1:c.3955+15T>C
  • NM_001407943.1:c.3952+15T>C
  • NM_001407944.1:c.3955+15T>C
  • NM_001407945.1:c.3955+15T>C
  • NM_001407946.1:c.3763+15T>C
  • NM_001407947.1:c.3763+15T>C
  • NM_001407948.1:c.3763+15T>C
  • NM_001407949.1:c.3763+15T>C
  • NM_001407950.1:c.3763+15T>C
  • NM_001407951.1:c.3763+15T>C
  • NM_001407952.1:c.3763+15T>C
  • NM_001407953.1:c.3763+15T>C
  • NM_001407954.1:c.3760+15T>C
  • NM_001407955.1:c.3760+15T>C
  • NM_001407956.1:c.3760+15T>C
  • NM_001407957.1:c.3763+15T>C
  • NM_001407958.1:c.3760+15T>C
  • NM_001407959.1:c.3715+15T>C
  • NM_001407960.1:c.3715+15T>C
  • NM_001407962.1:c.3712+15T>C
  • NM_001407963.1:c.3715+15T>C
  • NM_001407964.1:c.3952+15T>C
  • NM_001407965.1:c.3592+15T>C
  • NM_001407966.1:c.3208+15T>C
  • NM_001407967.1:c.3208+15T>C
  • NM_001407968.1:c.1492+15T>C
  • NM_001407969.1:c.1492+15T>C
  • NM_001407970.1:c.788-388T>C
  • NM_001407971.1:c.788-388T>C
  • NM_001407972.1:c.785-388T>C
  • NM_001407973.1:c.788-388T>C
  • NM_001407974.1:c.788-388T>C
  • NM_001407975.1:c.788-388T>C
  • NM_001407976.1:c.788-388T>C
  • NM_001407977.1:c.788-388T>C
  • NM_001407978.1:c.788-388T>C
  • NM_001407979.1:c.788-388T>C
  • NM_001407980.1:c.788-388T>C
  • NM_001407981.1:c.788-388T>C
  • NM_001407982.1:c.788-388T>C
  • NM_001407983.1:c.788-388T>C
  • NM_001407984.1:c.785-388T>C
  • NM_001407985.1:c.785-388T>C
  • NM_001407986.1:c.785-388T>C
  • NM_001407990.1:c.788-388T>C
  • NM_001407991.1:c.785-388T>C
  • NM_001407992.1:c.785-388T>C
  • NM_001407993.1:c.788-388T>C
  • NM_001408392.1:c.785-388T>C
  • NM_001408396.1:c.785-388T>C
  • NM_001408397.1:c.785-388T>C
  • NM_001408398.1:c.785-388T>C
  • NM_001408399.1:c.785-388T>C
  • NM_001408400.1:c.785-388T>C
  • NM_001408401.1:c.785-388T>C
  • NM_001408402.1:c.785-388T>C
  • NM_001408403.1:c.788-388T>C
  • NM_001408404.1:c.788-388T>C
  • NM_001408406.1:c.791-397T>C
  • NM_001408407.1:c.785-388T>C
  • NM_001408408.1:c.779-388T>C
  • NM_001408409.1:c.710-388T>C
  • NM_001408410.1:c.647-388T>C
  • NM_001408411.1:c.710-388T>C
  • NM_001408412.1:c.710-388T>C
  • NM_001408413.1:c.707-388T>C
  • NM_001408414.1:c.710-388T>C
  • NM_001408415.1:c.710-388T>C
  • NM_001408416.1:c.707-388T>C
  • NM_001408418.1:c.671-388T>C
  • NM_001408419.1:c.671-388T>C
  • NM_001408420.1:c.671-388T>C
  • NM_001408421.1:c.668-388T>C
  • NM_001408422.1:c.671-388T>C
  • NM_001408423.1:c.671-388T>C
  • NM_001408424.1:c.668-388T>C
  • NM_001408425.1:c.665-388T>C
  • NM_001408426.1:c.665-388T>C
  • NM_001408427.1:c.665-388T>C
  • NM_001408428.1:c.665-388T>C
  • NM_001408429.1:c.665-388T>C
  • NM_001408430.1:c.665-388T>C
  • NM_001408431.1:c.668-388T>C
  • NM_001408432.1:c.662-388T>C
  • NM_001408433.1:c.662-388T>C
  • NM_001408434.1:c.662-388T>C
  • NM_001408435.1:c.662-388T>C
  • NM_001408436.1:c.665-388T>C
  • NM_001408437.1:c.665-388T>C
  • NM_001408438.1:c.665-388T>C
  • NM_001408439.1:c.665-388T>C
  • NM_001408440.1:c.665-388T>C
  • NM_001408441.1:c.665-388T>C
  • NM_001408442.1:c.665-388T>C
  • NM_001408443.1:c.665-388T>C
  • NM_001408444.1:c.665-388T>C
  • NM_001408445.1:c.662-388T>C
  • NM_001408446.1:c.662-388T>C
  • NM_001408447.1:c.662-388T>C
  • NM_001408448.1:c.662-388T>C
  • NM_001408450.1:c.662-388T>C
  • NM_001408451.1:c.653-388T>C
  • NM_001408452.1:c.647-388T>C
  • NM_001408453.1:c.647-388T>C
  • NM_001408454.1:c.647-388T>C
  • NM_001408455.1:c.647-388T>C
  • NM_001408456.1:c.647-388T>C
  • NM_001408457.1:c.647-388T>C
  • NM_001408458.1:c.647-388T>C
  • NM_001408459.1:c.647-388T>C
  • NM_001408460.1:c.647-388T>C
  • NM_001408461.1:c.647-388T>C
  • NM_001408462.1:c.644-388T>C
  • NM_001408463.1:c.644-388T>C
  • NM_001408464.1:c.644-388T>C
  • NM_001408465.1:c.644-388T>C
  • NM_001408466.1:c.647-388T>C
  • NM_001408467.1:c.647-388T>C
  • NM_001408468.1:c.644-388T>C
  • NM_001408469.1:c.647-388T>C
  • NM_001408470.1:c.644-388T>C
  • NM_001408472.1:c.788-388T>C
  • NM_001408473.1:c.785-388T>C
  • NM_001408474.1:c.587-388T>C
  • NM_001408475.1:c.584-388T>C
  • NM_001408476.1:c.587-388T>C
  • NM_001408478.1:c.578-388T>C
  • NM_001408479.1:c.578-388T>C
  • NM_001408480.1:c.578-388T>C
  • NM_001408481.1:c.578-388T>C
  • NM_001408482.1:c.578-388T>C
  • NM_001408483.1:c.578-388T>C
  • NM_001408484.1:c.578-388T>C
  • NM_001408485.1:c.578-388T>C
  • NM_001408489.1:c.578-388T>C
  • NM_001408490.1:c.575-388T>C
  • NM_001408491.1:c.575-388T>C
  • NM_001408492.1:c.578-388T>C
  • NM_001408493.1:c.575-388T>C
  • NM_001408494.1:c.548-388T>C
  • NM_001408495.1:c.545-388T>C
  • NM_001408496.1:c.524-388T>C
  • NM_001408497.1:c.524-388T>C
  • NM_001408498.1:c.524-388T>C
  • NM_001408499.1:c.524-388T>C
  • NM_001408500.1:c.524-388T>C
  • NM_001408501.1:c.524-388T>C
  • NM_001408502.1:c.455-388T>C
  • NM_001408503.1:c.521-388T>C
  • NM_001408504.1:c.521-388T>C
  • NM_001408505.1:c.521-388T>C
  • NM_001408506.1:c.461-388T>C
  • NM_001408507.1:c.461-388T>C
  • NM_001408508.1:c.452-388T>C
  • NM_001408509.1:c.452-388T>C
  • NM_001408510.1:c.407-388T>C
  • NM_001408511.1:c.404-388T>C
  • NM_001408512.1:c.284-388T>C
  • NM_001408513.1:c.578-388T>C
  • NM_001408514.1:c.578-388T>C
  • NM_007294.4:c.4096+15T>CMANE SELECT
  • NM_007297.4:c.3955+15T>C
  • NM_007298.4:c.788-388T>C
  • NM_007299.4:c.788-388T>C
  • NM_007300.4:c.4096+15T>C
  • LRG_292t1:c.4096+15T>C
  • LRG_292:g.126564T>C
  • NC_000017.10:g.41243437A>G
  • NM_007294.3:c.4096+15T>C
Links:
dbSNP: rs1567788912
NCBI 1000 Genomes Browser:
rs1567788912
Molecular consequence:
  • NM_001407571.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407581.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407582.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407583.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407585.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407587.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407590.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407591.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407593.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407594.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407596.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407597.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407598.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407602.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407603.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407605.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407610.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407611.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407612.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407613.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407614.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407615.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407616.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407617.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407618.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407619.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407620.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407621.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407622.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407623.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407624.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407625.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407626.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407627.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407628.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407629.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407630.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407631.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407632.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407633.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407634.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407635.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407636.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407637.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407638.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407639.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407640.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407641.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407642.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407644.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407645.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407646.1:c.4087+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407647.1:c.4087+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407648.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407649.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407652.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407653.1:c.4018+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407654.1:c.4018+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407655.1:c.4018+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407656.1:c.4018+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407657.1:c.4018+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407658.1:c.4018+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407659.1:c.4015+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407660.1:c.4015+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407661.1:c.4015+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407662.1:c.4015+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407663.1:c.4018+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407664.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407665.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407666.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407667.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407668.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407669.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407670.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407671.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407672.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407673.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407674.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407675.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407676.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407677.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407678.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407679.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407680.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407681.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407682.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407683.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407684.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407685.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407686.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407687.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407688.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407689.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407690.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407691.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407692.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407694.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407695.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407696.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407697.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407698.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407724.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407725.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407726.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407727.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407728.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407729.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407730.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407731.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407732.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407733.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407734.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407735.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407736.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407737.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407738.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407739.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407740.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407741.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407742.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407743.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407744.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407745.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407746.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407747.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407748.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407749.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407750.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407751.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407752.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407838.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407839.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407841.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407842.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407843.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407844.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407845.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407846.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407847.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407848.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407849.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407850.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407851.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407852.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407853.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407854.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407858.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407859.1:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407860.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407861.1:c.4093+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407862.1:c.3895+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407863.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407874.1:c.3892+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407875.1:c.3892+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407879.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407881.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407882.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407884.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407885.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407886.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407887.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407889.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407894.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407895.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407896.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407897.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407898.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407899.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407900.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407902.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407904.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407906.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407907.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407908.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407909.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407910.1:c.3886+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407915.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407916.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407917.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407918.1:c.3883+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407919.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407920.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407921.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407922.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407923.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407924.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407925.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407926.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407927.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407928.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407929.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407930.1:c.3829+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407931.1:c.3829+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407932.1:c.3829+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407933.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407934.1:c.3829+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407935.1:c.3832+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407936.1:c.3829+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407937.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407938.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407939.1:c.3973+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407940.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407941.1:c.3970+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407942.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407943.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407944.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407945.1:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407946.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407947.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407948.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407949.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407950.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407951.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407952.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407953.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407954.1:c.3760+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407955.1:c.3760+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407956.1:c.3760+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407957.1:c.3763+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407958.1:c.3760+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407959.1:c.3715+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407960.1:c.3715+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407962.1:c.3712+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407963.1:c.3715+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407964.1:c.3952+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407965.1:c.3592+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407966.1:c.3208+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407967.1:c.3208+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407968.1:c.1492+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407969.1:c.1492+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407970.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407971.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407972.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407973.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407974.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407975.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407976.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407977.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407978.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407979.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407980.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407981.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407982.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407983.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407984.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407985.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407986.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407990.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407991.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407992.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407993.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408392.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408396.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408397.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408398.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408399.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408400.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408401.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408402.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408403.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408404.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408406.1:c.791-397T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408407.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408408.1:c.779-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408409.1:c.710-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408410.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408411.1:c.710-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408412.1:c.710-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408413.1:c.707-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408414.1:c.710-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408415.1:c.710-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408416.1:c.707-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408418.1:c.671-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408419.1:c.671-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408420.1:c.671-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408421.1:c.668-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408422.1:c.671-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408423.1:c.671-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408424.1:c.668-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408425.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408426.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408427.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408428.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408429.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408430.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408431.1:c.668-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408432.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408433.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408434.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408435.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408436.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408437.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408438.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408439.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408440.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408441.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408442.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408443.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408444.1:c.665-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408445.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408446.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408447.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408448.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408450.1:c.662-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408451.1:c.653-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408452.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408453.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408454.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408455.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408456.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408457.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408458.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408459.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408460.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408461.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408462.1:c.644-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408463.1:c.644-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408464.1:c.644-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408465.1:c.644-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408466.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408467.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408468.1:c.644-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408469.1:c.647-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408470.1:c.644-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408472.1:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408473.1:c.785-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408474.1:c.587-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408475.1:c.584-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408476.1:c.587-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408478.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408479.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408480.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408481.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408482.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408483.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408484.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408485.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408489.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408490.1:c.575-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408491.1:c.575-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408492.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408493.1:c.575-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408494.1:c.548-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408495.1:c.545-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408496.1:c.524-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408497.1:c.524-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408498.1:c.524-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408499.1:c.524-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408500.1:c.524-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408501.1:c.524-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408502.1:c.455-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408503.1:c.521-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408504.1:c.521-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408505.1:c.521-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408506.1:c.461-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408507.1:c.461-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408508.1:c.452-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408509.1:c.452-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408510.1:c.407-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408511.1:c.404-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408512.1:c.284-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408513.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408514.1:c.578-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_007294.4:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_007297.4:c.3955+15T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_007298.4:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_007299.4:c.788-388T>C - intron variant - [Sequence Ontology: SO:0001627]
  • NM_007300.4:c.4096+15T>C - intron variant - [Sequence Ontology: SO:0001627]

Condition(s)

Synonyms:
AllHighlyPenetrant
Identifiers:
MedGen: CN169374

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Assertion and evidence details

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Submission AccessionSubmitterReview Status
(Assertion method)		Clinical Significance
(Last evaluated)		OriginMethodCitations
SCV001338190Women's Health and Genetics/Laboratory Corporation of America, LabCorp
criteria provided, single submitter

(LabCorp Variant Classification Summary - May 2015)		Likely benign
(Feb 24, 2020) 		germlineclinical testing

PubMed (1)
[See all records that cite this PMID]

Citation Link

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Summary from all submissions

EthnicityOriginAffectedIndividualsFamiliesChromosomes testedNumber TestedFamily historyMethod
not providedgermlineunknownnot providednot providednot providednot providednot providedclinical testing

Citations

PubMed

Rapid mutation detection in complex genes by heteroduplex analysis with capillary array electrophoresis.

Velasco E, Infante M, Durán M, Esteban-Cardeñosa E, Lastra E, García-Girón C, Miner C.

Electrophoresis. 2005 Jun;26(13):2539-52.

PubMed [citation]
PMID:
15937982

Details of each submission

From Women's Health and Genetics/Laboratory Corporation of America, LabCorp, SCV001338190.1

#EthnicityIndividualsChromosomes TestedFamily HistoryMethodCitations
1not providednot providednot providednot providedclinical testing PubMed (1)

Description

Variant summary: BRCA1 c.4096+15T>C alters a non-conserved nucleotide located close to a canonical splice site and therefore could affect mRNA splicing, leading to a significantly altered protein sequence. 4/4 computational tools predict no significant impact on normal splicing. However, these predictions have yet to be confirmed by functional studies. The variant was absent in 250808 control chromosomes. The available data on variant occurrences in the general population are insufficient to allow any conclusion about variant significance. To our knowledge, no occurrence of c.4096+15T>C in individuals affected with Hereditary Breast and Ovarian Cancer and no experimental evidence demonstrating its impact on protein function have been reported. One report of its occurrence in a patient with breast cancer as part of a method validation study reported it as a "polymorphism" (Velasco_2005)(under an alternate legacy name c.4215+15T>C). Two clinical diagnostic laboratories have submitted clinical-significance assessments for this variant to ClinVar after 2014 without evidence for independent evaluation. Both laboratories classified the variant as benign/likely benign. Based on the evidence outlined above, the variant was classified as likely benign.

#SampleMethodObservation
OriginAffectedNumber testedTissuePurposeMethodIndividualsAllele frequencyFamiliesCo-occurrences
1germlineunknownnot providednot providednot providednot providednot providednot providednot provided

Last Updated: Jul 15, 2024