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Items: 1 to 100 of 1802

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
MSH2
Single nucleotide variant
(5 prime UTR variant)
Breast and/or ovarian cancer
+2 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(5 prime UTR variant +1 more)
Breast and/or ovarian cancer
+3 more
GConflicting classifications of pathogenicity
MSH2
(A2T)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome 1
GLikely benign
MSH2
(T8R)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
MSH2
(T8M)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
GBenign
MSH2
(F19L)
Single nucleotide variant
(missense variant +1 more)
not specified
+7 more
GConflicting classifications of pathogenicity
MSH2
(R21L)
Indel
(missense variant +1 more)
Breast and/or ovarian cancer
+2 more
GConflicting classifications of pathogenicity
MSH2
(F23L)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+5 more
GConflicting classifications of pathogenicity
MSH2
(T31S)
Single nucleotide variant
(missense variant +1 more)
Breast and/or ovarian cancer
+1 more
GUncertain significance
MSH2
(H46Q)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
GLikely benign
MSH2
Single nucleotide variant
(synonymous variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+4 more
GLikely benign
MSH2
Single nucleotide variant
(synonymous variant +2 more)
Hereditary nonpolyposis colorectal neoplasms
+7 more
GConflicting classifications of pathogenicity
MSH2
Duplication
(intron variant)
not provided
+4 more
GBenign/Likely benign
MSH2
Single nucleotide variant
(synonymous variant)
Breast and/or ovarian cancer
+2 more
GLikely benign
MSH2
(V78I +1 more)
Single nucleotide variant
(missense variant)
not provided
+4 more
GConflicting classifications of pathogenicity
MSH2
(R106K +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GBenign
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome
GBenign
MSH2
(N127S +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GBenign
MSH2
(L128V +1 more)
Single nucleotide variant
(missense variant)
not provided
+5 more
GConflicting classifications of pathogenicity
MSH2
(G137R +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
+5 more
GConflicting classifications of pathogenicity
MSH2
(I145M +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome 1
+9 more
GConflicting classifications of pathogenicity
MSH2
(V150I +1 more)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
+2 more
GUncertain significance
MSH2
(G157A +1 more)
Single nucleotide variant
(missense variant)
Hereditary nonpolyposis colorectal neoplasms
+6 more
GConflicting classifications of pathogenicity
MSH2
(D167H +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome 1
GBenign
MSH2
(I169V +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GLikely benign
MSH2
(N120S)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome
GBenign
MSH2
Single nucleotide variant
(intron variant)
Hereditary nonpolyposis colorectal neoplasms
+2 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(intron variant)
Hereditary nonpolyposis colorectal neoplasms
+3 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(intron variant)
not provided
+7 more
GConflicting classifications of pathogenicity
MSH2
(A272V +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GBenign
MSH2
(A305T +1 more)
Single nucleotide variant
(missense variant)
MSH2-related disorder
+5 more
GConflicting classifications of pathogenicity
MSH2
Deletion
Lynch syndrome 1
+6 more
GBenign/Likely benign
MSH2
Deletion
(intron variant)
Hereditary nonpolyposis colorectal neoplasms
+6 more
GConflicting classifications of pathogenicity
MSH2
Deletion
(intron variant)
not specified
+6 more
GConflicting classifications of pathogenicity
MSH2
Deletion
(intron variant)
Hereditary cancer-predisposing syndrome
+4 more
GBenign/Likely benign
MSH2
Deletion
(intron variant)
Hereditary cancer-predisposing syndrome
+4 more
GBenign/Likely benign
MSH2
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
MSH2
(T320A +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(intron variant)
Lynch syndrome
GBenign
MSH2
Single nucleotide variant
(intron variant)
not provided
+5 more
GConflicting classifications of pathogenicity
MSH2
(Q374R +1 more)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
+5 more
GConflicting classifications of pathogenicity
MSH2
(R382H +1 more)
Single nucleotide variant
(missense variant)
not provided
+5 more
GConflicting classifications of pathogenicity
MSH2
(L390F +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GBenign
MSH2
(R406Q +1 more)
Single nucleotide variant
(missense variant)
not provided
+7 more
GConflicting classifications of pathogenicity
MSH2
(Q419K +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GLikely benign
MSH2
Single nucleotide variant
(intron variant)
Lynch syndrome 1
+5 more
GBenign/Likely benign
MSH2
Single nucleotide variant
(intron variant)
Lynch syndrome 1
+5 more
GBenign/Likely benign
MSH2
(T441P +1 more)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
+6 more
GConflicting classifications of pathogenicity
MSH2
(M460V +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
+5 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(intron variant)
Lynch syndrome 1
GBenign
MSH2
(N465S +1 more)
Single nucleotide variant
(missense variant)
Hereditary nonpolyposis colorectal neoplasms
+3 more
GUncertain significance
MSH2
(D487E +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+6 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Hereditary cancer-predisposing syndrome
+1 more
GLikely benign
MSH2
Single nucleotide variant
(synonymous variant)
Breast and/or ovarian cancer
+7 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
not provided
+7 more
GConflicting classifications of pathogenicity
MSH2
(R524H +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
+6 more
GUncertain significance
MSH2
(T541I +1 more)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
+7 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(intron variant)
Hereditary nonpolyposis colorectal neoplasms
+3 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(intron variant)
Lynch syndrome
GBenign
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome
GBenign
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome
GLikely benign
MSH2
(T564A +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GBenign
MSH2
(I577T +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GLikely benign
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome
GLikely benign
MSH2
(N583S +1 more)
Single nucleotide variant
(missense variant)
Hereditary nonpolyposis colorectal neoplasms
+8 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Hereditary cancer-predisposing syndrome
+3 more
GLikely benign
MSH2
(M526I +1 more)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
GUncertain significance
MSH2
(N596S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+8 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Breast and/or ovarian cancer
+2 more
GLikely benign
MSH2
(Q629R +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome
GBenign
MSH2
(C641Y +1 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GConflicting classifications of pathogenicity
MSH2
(R614L +1 more)
Single nucleotide variant
(missense variant)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GUncertain significance
MSH2
Single nucleotide variant
(synonymous variant)
Breast and/or ovarian cancer
+4 more
GBenign/Likely benign
MSH2
(A689S +1 more)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
+2 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Breast and/or ovarian cancer
+5 more
GLikely benign
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome
GLikely benign
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome
+6 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(intron variant)
not provided
+4 more
GBenign/Likely benign
MSH2
Single nucleotide variant
(intron variant)
Hereditary nonpolyposis colorectal neoplasms
+3 more
GBenign/Likely benign
MSH2
Single nucleotide variant
(intron variant)
not provided
+6 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Breast and/or ovarian cancer
+7 more
GConflicting classifications of pathogenicity
MSH2
(N733del +1 more)
Microsatellite
(inframe_deletion)
Breast and/or ovarian cancer
+2 more
GUncertain significance
MSH2
Single nucleotide variant
(intron variant)
Breast and/or ovarian cancer
+5 more
GConflicting classifications of pathogenicity
MSH2
(E853G +1 more)
Single nucleotide variant
(missense variant)
Hereditary nonpolyposis colorectal neoplasms
+5 more
GUncertain significance
MSH2
(K872R +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome 1
+5 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Breast and/or ovarian cancer
+4 more
GLikely benign
MSH2
(I838V +1 more)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
+3 more
GConflicting classifications of pathogenicity
MSH2
(K909R +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GConflicting classifications of pathogenicity
MSH2
(Q910K +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
MSH2
(L911R +1 more)
Single nucleotide variant
(missense variant)
Lynch syndrome 1
+7 more
GConflicting classifications of pathogenicity
MSH2
Single nucleotide variant
(synonymous variant)
Lynch syndrome 1
GBenign
MSH6
Single nucleotide variant
(5 prime UTR variant)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
MSH6
Single nucleotide variant
(5 prime UTR variant +2 more)
Lynch syndrome
+5 more
GConflicting classifications of pathogenicity
MSH6
(Q4*)
Single nucleotide variant
(nonsense +1 more)
Breast and/or ovarian cancer
+8 more
GPathogenic/Likely pathogenic
MSH6
(S14F)
Single nucleotide variant
(missense variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+6 more
GConflicting classifications of pathogenicity
MSH6
(G32V)
Single nucleotide variant
(missense variant +1 more)
Breast and/or ovarian cancer
+3 more
GUncertain significance
MSH6
(A36V)
Single nucleotide variant
(missense variant +1 more)
not provided
+8 more
GConflicting classifications of pathogenicity
MSH6
(P42S)
Single nucleotide variant
(missense variant +1 more)
not provided
+6 more
GConflicting classifications of pathogenicity
MSH6
(G54A)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
GLikely benign
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