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Items: 1 to 100 of 1168

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
MLH1
Single nucleotide variant
(5 prime UTR variant)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant)
not provided
+3 more
GUncertain significance
MLH1
Single nucleotide variant
(5 prime UTR variant)
Breast and/or ovarian cancer
+6 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GUncertain significance
MLH1
Single nucleotide variant
(5 prime UTR variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
MLH1
(M1fs)
Deletion
(frameshift variant +2 more)
Hereditary cancer-predisposing syndrome
GLikely pathogenic
MLH1
Single nucleotide variant
(5 prime UTR variant)
Hereditary cancer-predisposing syndrome
GLikely benign
MLH1
Single nucleotide variant
(5 prime UTR variant)
Lynch syndrome
+1 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant)
not provided
+2 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant)
Hereditary cancer-predisposing syndrome
GUncertain significance
MLH1
Single nucleotide variant
(5 prime UTR variant)
not provided
+5 more
GUncertain significance
MLH1
Single nucleotide variant
(5 prime UTR variant)
not provided
+2 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant)
Breast and/or ovarian cancer
+4 more
GConflicting classifications of pathogenicity
MLH1
(M1L)
Single nucleotide variant
(5 prime UTR variant +2 more)
Hereditary cancer-predisposing syndrome
GLikely pathogenic
MLH1
(S2del)
Deletion
(inframe_deletion +2 more)
Colorectal cancer, hereditary nonpolyposis, type 2
+3 more
GUncertain significance
MLH1
(M1I)
Single nucleotide variant
(missense variant +2 more)
Lynch syndrome 1
GPathogenic
MLH1
(S2L)
Single nucleotide variant
(missense variant +1 more)
not specified
+5 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GLikely benign
MLH1
(F3L)
Single nucleotide variant
(missense variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GConflicting classifications of pathogenicity
MLH1
(F3L)
Single nucleotide variant
(missense variant +1 more)
not specified
+5 more
GConflicting classifications of pathogenicity
MLH1
(V4M)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GLikely benign
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GBenign/Likely benign
MLH1
(V7F)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(synonymous variant +1 more)
not specified
+2 more
GLikely benign
MLH1
(I8V)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
not provided
+5 more
GBenign/Likely benign
MLH1
(R9G)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
MLH1
(R9W)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
MLH1
(R9Q)
Single nucleotide variant
(missense variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
not provided
+3 more
GLikely benign
MLH1
(R10W)
Single nucleotide variant
(missense variant +1 more)
Colorectal cancer, hereditary nonpolyposis, type 2
+3 more
GUncertain significance
MLH1
(R10G)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
+3 more
GUncertain significance
MLH1
(R10L)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
MLH1
(R10Q)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GLikely benign
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
+4 more
GLikely benign
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Lynch syndrome
+2 more
GLikely benign
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GLikely benign
MLH1
(D12E)
Single nucleotide variant
(missense variant +1 more)
Colorectal cancer, hereditary nonpolyposis, type 2
+3 more
GUncertain significance
MLH1
(E13Q)
Single nucleotide variant
(missense variant +1 more)
not specified
+3 more
GUncertain significance
MLH1
(E13K)
Single nucleotide variant
(missense variant +1 more)
not provided
+5 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Breast and/or ovarian cancer
+7 more
GConflicting classifications of pathogenicity
MLH1
(V15L)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
MLH1
(V15A)
Single nucleotide variant
(missense variant +1 more)
Colorectal cancer, hereditary nonpolyposis, type 2
+3 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Lynch syndrome
+4 more
GLikely benign
MLH1
(V16L)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+5 more
GUncertain significance
MLH1
(V16M)
Single nucleotide variant
(missense variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GUncertain significance
MLH1
(V16G)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
not provided
+3 more
GLikely benign
MLH1
(R18C)
Single nucleotide variant
(missense variant +1 more)
not specified
+6 more
GConflicting classifications of pathogenicity
MLH1
(I19M)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
MLH1
(A20T)
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
MLH1
(A20V)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GLikely benign
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Lynch syndrome
+2 more
GLikely benign
MLH1
(G22A)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
GBenign
MLH1
(E23*)
Single nucleotide variant
(nonsense +1 more)
Lynch syndrome
GPathogenic
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Breast and/or ovarian cancer
+6 more
GBenign/Likely benign
MLH1
(E23D)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
+3 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GLikely benign
MLH1
(R27G)
Single nucleotide variant
(missense variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GUncertain significance
MLH1
(R27W)
Single nucleotide variant
(missense variant +1 more)
not specified
+4 more
GUncertain significance
MLH1
(R27Q)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GConflicting classifications of pathogenicity
MLH1
(P28S)
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
MLH1
(P28L)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
GPathogenic
MLH1
(A29D)
Single nucleotide variant
(missense variant +1 more)
Colorectal cancer, hereditary nonpolyposis, type 2
+2 more
GUncertain significance
MLH1
(N30S)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
MLH1
(A31T)
Single nucleotide variant
(missense variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+5 more
GUncertain significance
MLH1
(A31C)
Indel
(missense variant +1 more)
not provided
+7 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
GLikely benign
MLH1
(I32V)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
GLikely benign
MLH1
(I32M)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
+2 more
GUncertain significance
MLH1
(K33N)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
MLH1
(E34D)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
MLH1
(I36T)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +1 more)
Lynch syndrome
+4 more
GLikely benign
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+3 more
GLikely benign
MLH1
(N38K)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
GPathogenic
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Lynch syndrome
+4 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Lynch syndrome
GPathogenic
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+2 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+2 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GLikely benign
MLH1
Deletion
(5 prime UTR variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GLikely benign
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary nonpolyposis colorectal neoplasms
+1 more
GLikely benign
MLH1
Duplication
(5 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
GLikely benign
MLH1
Single nucleotide variant
(5 prime UTR variant +1 more)
not specified
+2 more
GBenign/Likely benign
MLH1
Single nucleotide variant
(intron variant)
Hereditary nonpolyposis colorectal neoplasms
+2 more
GLikely benign
MLH1
Single nucleotide variant
(intron variant)
not specified
+4 more
GConflicting classifications of pathogenicity
MLH1
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
GLikely benign
MLH1
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
+2 more
GLikely benign
MLH1
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
GLikely benign
MLH1
(A42V)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
MLH1
Single nucleotide variant
(synonymous variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GLikely benign
MLH1
Single nucleotide variant
(synonymous variant +2 more)
Hereditary cancer-predisposing syndrome
GLikely benign
MLH1
(T45fs)
Deletion
(frameshift variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GPathogenic
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